Evidence map›Paper›PMID 33731329›Full record

ArticleBMJ open respiratory research2021

Clinical characteristics and outcomes of adult patients admitted with COVID-19 in East London: a retrospective cohort analysis.

Daryl Cheng, Claire Calderwood, Erik Skyllberg, Adam Ainley

Abstract read
In one paragraph

Article in BMJ open respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022
    Pooled it
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  11. Prevalence of persistent symptoms after having COVID-19 in a cohort in Suriname.Revista panamericana de salud publica = Pan American journal of public health · 2023
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  19. Mortality and Years of Potential Life Lost Due to COVID-19 in Brazil.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daryl ChengRespiratory Department, Barking Havering and Redbridge University Hospitals NHS Trust, Romford, UK.ORCID 0000-0001-9906-4298
Claire CalderwoodRespiratory Department, Barking Havering and Redbridge University Hospitals NHS Trust, Romford, UK.
Erik SkyllbergRespiratory Department, Barking Havering and Redbridge University Hospitals NHS Trust, Romford, UK.
Adam AinleyRespiratory Department, Barking Havering and Redbridge University Hospitals NHS Trust, Romford, UK adam.ainley@nhs.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDescriptions of clinical characteristics of patients hospitalised withCOVID-19, their clinical course and short-term inpatient and outpatient outcomes in deprived urban populations in the UK are still relatively sparse. We describe the epidemiology, clinical course, experience of non-invasive ventilation and intensive care, mortality and short-term sequelae of patients admitted to two large District General Hospitals across a large East London National Health Service Trust during the first wave of the pandemic.

methodsA retrospective analysis was carried out on a cohort of 1946 patients with a clinical or laboratory diagnosis of COVID-19, including descriptive statistics and survival analysis. A more detailed analysis was undertaken of a subset of patients admitted across three respiratory units in the trust.

resultsIncreasing age, male sex and Asian ethnicity were associated with worse outcomes. Increasing severity of chest X-ray abnormalities trended with mortality. Radiological changes persisted in over 50% of cases at early follow-up (6 weeks). Ongoing symptoms including hair loss, memory impairment, breathlessness, cough and fatigue were reported in 70% of survivors, with 39% of patients unable to return to work due to ongoing symptoms.

conclusionsUnderstanding the acute clinical features, course of illness and outcomes of COVID-19 will be crucial in understanding the effect of differences in risk, as well as the effectiveness of new interventions and vaccination between the successive waves of the pandemic.

Indexed as

AgedAged, 80 and overAge FactorsAlopeciaCohort StudiesCoughCOVID-19DyspneaEthnicityFatigueFemaleHospital MortalityHumansIntensive Care UnitsLondonMaleclinical epidemiologyimaging/CT MRI etcnon invasive ventilationpneumoniarespiratory infectionviral infection

Identifiers

PMID33731329
PMCPMC7976675

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.