ArticleBMC pediatrics2021
Prevalence of functional gastrointestinal disorders in infants and young children in China.
Article in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and influencing factors of functional constipation in Chinese children and adolescents: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Adjunctive efficacy of Bifidobacterium animalis subsp. lactis XLTG11 for functional constipation in children.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Trial
- Safety and tolerance assessment of milk fat globule membrane-enriched infant formulas in healthy term Chinese infants: a randomised multicenter controlled trial.BMC pediatrics · 2022Trial
- Beta-casein in human milk is associated with infant stool frequency: A pilot proteomics study.Physiological reports · 2026Article
- Rome IV Functional Constipation in Childhood: Early-Life Factors and Dietary Habits in a Southeast Asian Clinical Setting.Journal of paediatrics and child health · 2026Article
- Beyond the Organic: A Biopsychosocial Analysis of Pediatric Functional Gastrointestinal Disorders-A Retrospective Chart Review.Children (Basel, Switzerland) · 2026Article
- Development and validation of a risk prediction model for functional constipation in school-aged children.BMC pediatrics · 2026Article
- Kinetics of resilience with onset and remission of pediatric functional gastrointestinal disorders: A longitudinal study.iScience · 2026Article
- Functional constipation in Thai infants and toddlers: The role of genetic-gut-brain interaction and fiber supplementation.World journal of clinical pediatrics · 2026Article
- Overlap of Structural Gastrointestinal Disorders in Children With Disorders of Gut-Brain Interaction.Neurogastroenterology and motility · 2026Review
- [Prevalence and Influencing Factors of Functional Gastrointestinal Disorders Among Infants Aged 0 to 9 Months With Gastrointestinal Discomfort in China: A Multicenter Cross-Sectional Survey].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Article
- Prevalence of constipation in children visiting MCH clinic Al-Ahsa eastern region of Saudi Arabia cross-sectional study.Journal of family medicine and primary care · 2025Article
- Parents' preferences for herbal supplements in managing functional gastrointestinal disorders.BMC complementary medicine and therapies · 2025Article
- Prevalence of functional diarrhea in children and adolescents.Neurogastroenterology and motility · 2025Article
- Functional Diarrhea in Children.Indian journal of pediatrics · 2024Review
- Prevalence and determinants of constipation in children in Asia: a systematic review and meta-analysis.EClinicalMedicine · 2024Article
- The ten "hard" questions in pediatric functional constipation.Italian journal of pediatrics · 2024Review
- Retrospective Study on the Association Between Climate Factors and Infant Colic in Beijing (2021-2022).Journal of multidisciplinary healthcare · 2024Article
- Functional gastrointestinal disorders in Jordanian infants: a pilot study.Przeglad gastroenterologiczny · 2024Article
- Knowledge, attitude, and practice of Chinese parents with infants (aged 0-3 years) toward immunity, gut microbiota and biotics: a comprehensive study.Frontiers in immunology · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of functional gastrointestinal disorders (FGIDs) in children, particularly from Asia, is largely unknown. There are not many studies done in Asia especially using the Rome IV criteria. The aim of this study is to assess the prevalence of FGIDs in infants and young children in a representative sample in China.
methodsA prospective, cross-sectional, community-based survey was conducted among healthy infants and young children between the ages of 0-4 years in Jinhua and Shanghai, China. A total of 2604 subjects (1300 subjects from Jinhua and 1304 subjects from Shanghai) completed a validated questionnaire on pediatric gastrointestinal symptoms. FGIDs in infants and young children were diagnosed using the Rome IV criteria.
resultsAccording to the Rome IV criteria, the prevalence of having a FGID in Chinese infants and young children is 27.3%. Infant regurgitation (33.9%) was the most common FGID among the 0-6 months old while functional constipation (7.0%) was the most common among the 1-4 years old. Risk factor analysis revealed that prevalence of infantile colic was higher with better maternal education and low birth weight. Prevalence of infantile regurgitation was significantly greater in males, living in a rural area, being exclusively breast fed at least up to 4 months and starting formula feeds within the first month. The risk of functional constipation was lower for infants who were delivered vaginally.
conclusionsInfantile regurgitation was the most common FGID in Chinese infants while functional constipation was most prevalent among young Chinese children.
trial registrationNetherlands Trial Registry Identifier: NL6973/NTR7161 .
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