ArticleEnvironmental analysis, health and toxicology2021
The current status of studies of human exposure assessment of microplastics and their health effects: a rapid systematic review.
Article in Environmental analysis, health and toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Toxicological effects of micro/nano-plastics on mouse/rat models: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Isolation and characterization of microplastics from human blood samples by confocal RAMAN microscopy.MethodsX · 2026Article
- Do microplastics play a role in the pathogenesis of neurodegenerative diseases? Shared pathophysiological pathways for Alzheimer's and Parkinson's disease.Molecular and cellular biochemistry · 2026Review
- Micro- and nanoplastic exposure as an emerging risk factor for depressive-like phenotypes across species: a systematic review.Frontiers in toxicology · 2026Review
- Review
- Microplastic exposure induces epithelial barrier alterations and increases collagen deposition in a 3D human endometrial model in vitro.Journal of assisted reproduction and genetics · 2025Article
- Detection of microplastics in the feline placenta and fetus.PloS one · 2025Article
- Microplastics in the Human Body: Exposure, Detection, and Risk of Carcinogenesis: A State-of-the-Art Review.Cancers · 2024Review
- Microplastics Derived from Food Packaging Waste-Their Origin and Health Risks.Materials (Basel, Switzerland) · 2023Review
- The Minderoo-Monaco Commission on Plastics and Human Health.Annals of global health · 2023Review
- Article
- Microplastics detected in cirrhotic liver tissue.EBioMedicine · 2022Article
- In Vivo Toxicity and Pharmacokinetics of Polytetrafluoroethylene Microplastics in ICR Mice.Polymers · 2022Article
- Screening and prioritization of nano- and microplastic particle toxicity studies for evaluating human health risks - development and application of a toxicity study assessment tool.Microplastics and nanoplastics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This rapid systematic review aims to summarize studies of human exposure to microplastics (MPs) and their health effects. For the systematic literature review, we separately searched for review articles and original articles published from 2000 to 2019 in the PubMed, NDSL, KMBASE, and Cochrane databases. A total of 276 review articles and 475 original articles were independently evaluated and eligibility of each article was assessed by two researchers. Finally, 8 review articles and 13 original articles were selected for analysis. There was no standardized methodology for determining human exposure to MPs. Therefore, the size, shape, color, and chemical composition of MPs were considered as factors that affected human exposure to MP. We ascertained that human exposure to MPs occurs through two major routes: inhalation and ingestion. The general population can be exposed to MPs through the food chain, food, and mineral water. Thus, there are multiple scenarios for the exposure process. The only exposure marker in humans is the detection and measurement of MPs in feces. Health effects of human exposure to MPs include respiratory effects from inhalation, digestive effects from ingestion, oxidative stress, and cancer. However, there are few studies of the effects of MP exposure in the general population. Based on a systematic review, we propose a standardized methodology to identify various exposure scenarios to facilitate studies of human exposure to MPs and their health effects.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.