Evidence map›Paper›PMID 33730781›Full record

ArticleJournal of bone metabolism2021

Physical Activity and Bone Health in Men: A Systematic Review and Meta-Analysis.

Maureen C Ashe, Isis Kelly Dos Santos, Nicola Y Edward, Laura A Burnett, Rosanne Barnes, Lena Fleig, Joseph H Puyat, Joanna E M Sale, Heather A McKay, Lora M Giangregorio

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bone metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Approach to personalizing the treatment of osteoporosis.The Journal of clinical endocrinology and metabolism · 2026
    Review
  9. Article
  10. Physical Activity and Oxidative Stress in Aging.Antioxidants (Basel, Switzerland) · 2024
    Review
  11. Exercise and Musculoskeletal Health in Men With Low Bone Mineral Density: A Systematic Review.Archives of rehabilitation research and clinical translation · 2024
    Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maureen C AsheCentre for Hip Health and Mobility, The University of British Columbia, Vancouver, Canada.
Isis Kelly Dos SantosDepartment of Health Sciences, Federal University of Rio Grande do Norte, Natal, Brazil.
Nicola Y EdwardCentre for Hip Health and Mobility, The University of British Columbia, Vancouver, Canada.
Laura A BurnettCentre for Hip Health and Mobility, The University of British Columbia, Vancouver, Canada.
Rosanne BarnesCentre for Hip Health and Mobility, The University of British Columbia, Vancouver, Canada.
Lena FleigDepartment of Psychology, MSB Medical School Berlin, Berlin, Germany.
Joseph H PuyatSchool of Population and Public Health, The University of British Columbia, Vancouver, Canada.
Joanna E M SaleMusculoskeletal Health and Outcomes Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health, Toronto, Canada.
Heather A McKayCentre for Hip Health and Mobility, The University of British Columbia, Vancouver, Canada.
Lora M GiangregorioDepartment of Kinesiology and Schlegel Research Institute for Aging, University of Waterloo, Waterloo, Canada.

Funding

CIHRExerciseMaleMusculoskeletal diseases
6 · The paper itself

Abstract

backgroundResearch on osteoporosis and physical activity often focuses on women. We aimed to conduct a systematic review to assess the benefits and harms of physical activity interventions for men's bone health.

methodsWe used standard methods and searched for randomized controlled trials (RCTs) (duration, ≥6 months) published in all languages across multiple databases and trial registries. The last search was conducted on July 22, 2020.

resultsWe included 11 studies (14 publications), resulting in a sample of N=723 men (range, 17-132 participants). We found low-certainty evidence that physical activity has little influence on the areal bone mineral density (aBMD) at the total hip (5 RCTs, N=324; mean difference [MD], 0.03 [95 confidence interval (CI), 0.01 to 0.05]) and little or no influence on the aBMD at the femoral neck (3 RCTs, N=186; MD, 0.00 [95% CI, -0.04 to 0.04]), lumbar spine (3 RCTs; N=213; MD, 0.05 [95% CI, -0.01 to 0.11]), and whole body (4 RCTs, N=203; MD, -0.00 [95% CI, -0.03 to 0.02]).

conclusionsWe found low-certainty evidence that physical activity (≥6 months) has some effect on the total hip in men, but new evidence may change this finding. This review highlights the gap in the evidence on specific intervention prescriptions that can benefit the bone geometry, structure, microarchitecture, and, ultimately, bone strength in men. Future research should engage in comprehensive reporting of harms, quality of life outcomes, advanced imaging findings, and long-term interventions.

Indexed as

Bone and bones

Identifiers

PMID33730781
PMCPMC7973404

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.