Evidence map›Paper›PMID 33730756›Full record

ReviewJournal of Crohn's & colitis2021

Results of the Seventh Scientific Workshop of ECCO: Precision Medicine in IBD-Disease Outcome and Response to Therapy.

Bram Verstockt, Nurulamin M Noor, Urko M Marigorta, Polychronis Pavlidis, Parakkal Deepak, Ryan C Ungaro, Scientific Workshop Steering Committee

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of Crohn's & colitis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 76 citations in OpenAlex.

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  12. Understanding the therapeutic toolkit for inflammatory bowel disease.Nature reviews. Gastroenterology & hepatology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 9 institutions in 6 countries.

Bram VerstocktUniversity Hospitals Leuven Department of Gastroenterology and Hepatology, KU Leuven, Leuven, Belgium.ORCID 0000-0003-3898-7093
Nurulamin M NoorDepartment of Gastroenterology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Trust, Cambridge, UK.ORCID 0000-0003-3426-6408
Urko M MarigortaIntegrative Genomics Lab, Center for Cooperative Research in Biosciences [CIC bioGUNE], Basque Research and Technology Alliance [BRTA], Derio, Spain.
Polychronis PavlidisDepartment of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Parakkal DeepakInflammatory Bowel Diseases Center, Washington University in Saint Louis School of Medicine, St Louis, MO, USA.ORCID 0000-0002-3436-9784
Ryan C UngaroHenry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Scientific Workshop Steering Committee
Cambridge University Hospitals NHS Foundation Trust · GBCleveland Clinic Lerner College of Medicine · USHospital Beatriz Ângelo · PTIcahn School of Medicine at Mount Sinai · USIkerbasque · ESKing's College London · GBKU Leuven · BEUniversity Hospital of Zurich · CHWashington University in St. Louis · US

Funding

Assessing Predictors of Response to Anti-Tumor Necrosis Alpha Therapy in Early Crohns DiseaseK23DK111995 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI UNGARO, RYAN · 2019 to 2023
$948k
NIDDK NIH HHS K23 DK111995
6 · The paper itself

Abstract

Inflammatory bowel diseases [IBD] are a heterogeneous spectrum with two extreme phenotypes, Crohn's disease [CD] and ulcerative colitis [UC], which both represent numerous phenotypical variations. Hence, we should no longer approach all IBD patients similarly, but rather aim to rethink clinical classifications and modify treatment algorithms to usher in a new era of precision medicine in IBD. This scientific ECCO workshop aims to provide a state-of-the-art overview on prognostic and predictive markers, shed light on key questions in biomarker development, propose best practices in IBD biomarker development [including trial design], and discuss the potential for multi-omic data integration to help drive further advances to make precision medicine a reality in IBD.

Indexed as

Precision MedicineAlgorithmsBiomarkersHumansInflammatory Bowel DiseasesOutcome Assessment, Health CarePrognosisBiomarkersdisease outcomedisease prognosisinflammatory bowel diseasespersonalised medicinePrecision medicineresponse to therapy

Identifiers

PMID33730756
PMCPMC8681673
OpenAlexW3136576223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.