Evidence map›Paper›PMID 33730577›Full record

ArticleCell reports2021

High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons.

David I Levi, Joshua C Wyrosdic, Amirah-Iman Hicks, Mary Ann Andrade, Glenn M Toney, Masha Prager-Khoutorsky, Charles W Bourque

Abstract read
In one paragraph

Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
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  4. Article
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  6. Article
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  8. Article
  9. Article
  10. Review
  11. Central regulation of body fluid homeostasis.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2022
    Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David I LeviBrain Repair and Integrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal General Hospital, 1650 Cedar Avenue, Montreal, QC H3G1A4, Canada.
Joshua C WyrosdicBrain Repair and Integrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal General Hospital, 1650 Cedar Avenue, Montreal, QC H3G1A4, Canada.
Amirah-Iman HicksDepartment of Physiology, McGill University, 3644 Promenade Sir William Osler, Montreal, QC H3G1Y6, Canada.
Mary Ann AndradeDepartment of Cellular and Integrative Physiology, University of Texas Health Sciences Centre San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Glenn M ToneyDepartment of Cellular and Integrative Physiology, University of Texas Health Sciences Centre San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Masha Prager-KhoutorskyDepartment of Physiology, McGill University, 3644 Promenade Sir William Osler, Montreal, QC H3G1Y6, Canada. Electronic address: masha.prager-khoutorsky@mcgill.ca.
Charles W BourqueBrain Repair and Integrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal General Hospital, 1650 Cedar Avenue, Montreal, QC H3G1A4, Canada. Electronic address: charles.bourque@mcgill.ca.

Funding

Neurohumoral Adaptations to Chronic Intermittent Hypoxia: Insights into the Pathophysiology of Sleep ApneaP01HL088052 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI TONEY, GLENN M · 2008 to 2019
$18.8M
Mechanisms of Synaptic Homeostasis Governing Pre-Sympathetic Neurons in the Hypothalamic Paraventricular NucleusR01NS115072 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI TONEY, GLENN M · 2020 to 2024
$2.4M
CIHR FDN-143337NHLBI NIH HHS P01 HL088052NINDS NIH HHS R01 NS115072
6 · The paper itself

Abstract

High dietary salt increases arterial pressure partly through activation of magnocellular neurosecretory cells (MNC

Indexed as

OsmosisAngiotensin IIAnimalsCell MembraneCytoskeletonDisease Models, AnimalExcitatory Postsynaptic PotentialsHypertensionMaleMechanotransduction, CellularNeuronsProbabilityRatsRats, WistarSodium Chloride, DietarySynapsesAngiotensin IISodium Chloride, DietaryVasopressinsangiotensin IIhypertensionmechanosensitivityosmosensitivitysupraoptic nucleusvasopressin

Identifiers

PMID33730577
PMCPMC8049100

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.