ArticleNeuron2021
Identification and disruption of a neural mechanism for accumulating prospective metacognitive information prior to decision-making.
Article in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Towards an integrative neuroscience of metacognition.Nature reviews. Neuroscience · 2026Review
- Brain activity, disruption and connectivity comparisons identify origins of human metacognition in other primates.Nature human behaviour · 2026Article
- Decision-making trades off learned and perceived information.PNAS nexus · 2026Article
- Computational origins of cortical brain circuits for social cognition.Nature reviews. Neuroscience · 2026Review
- The neurological implications of metacognition.Frontiers in psychology · 2026Article
- Decision-making trades off learned and perceived information.Research square · 2025Article
- Functional-structural co-dependent brain mapping of metamemory in amnestic mild cognitive impairment.Alzheimer's research & therapy · 2025Article
- Article
- Multimodal trajectory prediction for intelligent connected vehicles in complex road scenarios based on causal reasoning and driving cognition characteristics.Scientific reports · 2025Article
- Asymmetric projection of introspection reveals a behavioural and neural mechanism for interindividual social coordination.Nature communications · 2025Article
- Implicit manifestation of prospective metacognition in betting choices enhances its efficiency compared to explicit expression.Frontiers in human neuroscience · 2025Article
- Neural Correlates of Metacognition Impairment in Opioid Addiction.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Multiscale chemogenetic dissection of fronto-temporal top-down regulation for object memory in primates.Nature communications · 2024Article
- The neural representation of metacognition in preferential decision-making.Human brain mapping · 2024Article
- Article
- Review
- Confidence guides priority between forthcoming tasks.Scientific reports · 2021Article
- Article
- Know thy future self.Nature reviews. Neuroscience · 2021Article
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8 authors.
Funding
Abstract
More than one type of probability must be considered when making decisions. It is as necessary to know one's chance of performing choices correctly as it is to know the chances that desired outcomes will follow choices. We refer to these two choice contingencies as internal and external probability. Neural activity across many frontal and parietal areas reflected internal and external probabilities in a similar manner during decision-making. However, neural recording and manipulation approaches suggest that one area, the anterior lateral prefrontal cortex (alPFC), is highly specialized for making prospective, metacognitive judgments on the basis of internal probability; it is essential for knowing which decisions to tackle, given its assessment of how well they will be performed. Its activity predicted prospective metacognitive judgments, and individual variation in activity predicted individual variation in metacognitive judgments. Its disruption altered metacognitive judgments, leading participants to tackle perceptual decisions they were likely to fail.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.