Evidence map›Paper›PMID 33730519›Full record

Trial reportAmerican journal of respiratory and critical care medicine2021

The Airway Microbiota Modulates Effect of Azithromycin Treatment for Episodes of Recurrent Asthma-like Symptoms in Preschool Children: A Randomized Clinical Trial.

Jonathan Thorsen, Jakob Stokholm, Morten Arendt Rasmussen, Martin Steen Mortensen, Asker Daniel Brejnrod, Mathis Hjelmsø, Shiraz Shah, Bo Chawes, Klaus Bønnelykke, Søren Johannes Sørensen and 1 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. Article
  3. Observational
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. The Microbiota in Children and Adolescents with Asthma.Children (Basel, Switzerland) · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Precision Medicine in Asthma Therapy.Handbook of experimental pharmacology · 2023
    Article
  18. Winds of change a tale of: asthma and microbiome.Frontiers in microbiology · 2023
    Review
  19. Therapeutic Targeting of the Respiratory Microbiome.American journal of respiratory and critical care medicine · 2022
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jonathan ThorsenCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital.ORCID 0000-0003-0200-0461
Jakob StokholmCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital.ORCID 0000-0003-4989-9769
Morten Arendt RasmussenCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital.ORCID 0000-0001-7431-5206
Martin Steen MortensenSection for Microbiology, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark; and.ORCID 0000-0001-5483-7533
Asker Daniel BrejnrodSection for Microbiology, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark; and.ORCID 0000-0002-1327-2051
Mathis HjelmsøCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital.ORCID 0000-0001-9716-624X
Shiraz ShahCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital.ORCID 0000-0002-4665-577X
Bo ChawesCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital.ORCID 0000-0001-6846-6243
Klaus BønnelykkeCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital.ORCID 0000-0003-2003-1018
Søren Johannes SørensenSection for Microbiology, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark; and.ORCID 0000-0001-6227-9906
Hans BisgaardCopenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital.ORCID 0000-0003-4131-7592
Gentofte Hospital · DKUniversity of Copenhagen · DKNovo Nordisk Foundation · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsAsthmaAzithromycinChild, PreschoolCohort StudiesFemaleHumansInfantMaleMicrobiotaProspective StudiesReinfectionAnti-Bacterial AgentsAzithromycin16S sequencingasthmaazithromycinmicrobiotapediatrics

Identifiers

PMID33730519
OpenAlexW3139208701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.