Evidence map›Paper›PMID 33730418›Full record

ArticleNeuropathology and applied neurobiology2021

Atypical astroglial pTDP-43 pathology in astroglial predominant tauopathy.

Ellen Gelpi, Iban Aldecoa, Dolores Lopez-Villegas, Maria Teresa Abellan-Vidal, Pilar Mercadel-Fañanas, Juan Fortea, Roser Ribosa, Estrella Morenas, Beatriz Gomez-Anson, Laura Molina-Porcel and 8 more

Abstract readCase ReportsLetter
In one paragraph

Article in Neuropathology and applied neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Classification of diseases with accumulation of Tau protein.Neuropathology and applied neurobiology · 2022
    Article
  7. Article
  8. Multiple system aging-related tau astrogliopathy with complex proteinopathy in an oligosymptomatic octogenarian.Neuropathology : official journal of the Japanese Society of Neuropathology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ellen GelpiNeurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Spain.ORCID 0000-0003-2948-4187
Iban AldecoaNeurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Spain.
Dolores Lopez-VillegasCognitive Disorders and Psychogeriatry, Institut de Neuropsiquiatria i Addiccions, Centre Emili Mira, Parc de Salut Mar, Barcelona, Spain.
Maria Teresa Abellan-VidalCognitive Disorders and Psychogeriatry, Institut de Neuropsiquiatria i Addiccions, Centre Emili Mira, Parc de Salut Mar, Barcelona, Spain.
Pilar Mercadel-FañanasCognitive Disorders and Psychogeriatry, Institut de Neuropsiquiatria i Addiccions, Centre Emili Mira, Parc de Salut Mar, Barcelona, Spain.
Juan ForteaNeurology Department, Hospital de la Santa Creu i St Pau, St Pau research Institute, Barcelona, Spain.
Roser RibosaNeurology Department, Hospital de la Santa Creu i St Pau, St Pau research Institute, Barcelona, Spain.
Estrella MorenasNeurology Department, Hospital de la Santa Creu i St Pau, St Pau research Institute, Barcelona, Spain.
Beatriz Gomez-AnsonRadiology Department, Hospital de la Santa Creu i St Pau, Barcelona, Spain.
Laura Molina-PorcelNeurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Spain.
Teresa XimelisNeurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Spain.
Sergi BorregoNeurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Spain.ORCID 0000-0003-2557-0010
Anna AntonellAlzheimer's disease and other cognitive disorders unit, Neurology Department, Hospital Clinic I Provincial de Barcelona and Institut d'Investigacions Biomediques August Pi I Sunyer, Barcelona, Spain.
Anne Rovelet-LecruxUniversité de Rouen, Institut de Recherche et d'Innovation Biomédicale (IRIB), Mont-Saint-Aignan, France.
Sigrid KlotzDivision of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Vienna, Austria.
Pol Andres-BenitoDepartment of Pathology and Experimental Therapeutics, University of Barcelona, Bellvitge University Hospital-IDIBELL, CIBERNED, Hospitalet de Llobregat, Spain.
Raquel Sanchez-ValleNeurological Tissue Bank of the Biobank-Hospital Clinic-IDIBAPS, Barcelona, Spain.
Isidre FerrerDepartment of Pathology and Experimental Therapeutics, University of Barcelona, Bellvitge University Hospital-IDIBELL, CIBERNED, Hospitalet de Llobregat, Spain.ORCID 0000-0001-9888-8754

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We observed atypical astrocytic pTDP-43 pathology in astroglial predominant tauopathy.

Indexed as

AgedAstrocytesC9orf72 ProteinDNA-Binding ProteinsFemaleFrontotemporal DementiaFrontotemporal Lobar DegenerationHumansInclusion BodiesMiddle AgedNeuronsTauopathiesC9orf72 ProteinDNA-Binding Proteinsastroglial tauopathyFTLD-Tauglia limitans/perivascular gliapTDP-43TDP-43

Identifiers

PMID33730418
PMCPMC9292602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.