ArticleMedical physics2021
Technical Note: Single-pulse beam characterization for FLASH-RT using optical imaging in a water tank.
Article in Medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- A systematic review of electron FLASH dosimetry and beam control mechanisms utilized with modified non-clinical LINACs.Journal of applied clinical medical physics · 2025Pooled it
- Development of in situ dosimetry for FLASH proton radiotherapy via organic scintillating fibers.The British journal of radiology · 2026Article
- Radioluminescence 3D dose reconstruction for FLASH and conventional radiotherapy.Scientific reports · 2026Article
- High spatiotemporal resolution scintillation imaging of pulsed pencil beam scanning proton beams produced by a gantry-mounted synchrocyclotron.Medical physics · 2024Article
- Investigation of Photodynamic Therapy Promoted by Cherenkov Light Activated Photosensitizers-New Aspects and Revelations.Pharmaceutics · 2024Article
- Characterization of a diode dosimeter for UHDR FLASH radiotherapy.Medical physics · 2023Article
- Image guidance for FLASH radiotherapy.Medical physics · 2022Article
- Individual pulse monitoring and dose control system for pre-clinical implementation of FLASH-RT.Physics in medicine and biology · 2022Article
- A Diamond-Based Dose-per-Pulse X-ray Detector for Radiation Therapy.Materials (Basel, Switzerland) · 2021Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
purposeHigh dose rate conditions, coupled with problems related to small field dosimetry, make dose characterization for FLASH-RT challenging. Most conventional dosimeters show significant dependence on dose rate at ultra-high dose rate conditions or fail to provide sufficiently fast temporal data for pulse to pulse dosimetry. Here fast 2D imaging of radioluminescence from a water and quinine phantom was tested for dosimetry of individual 4 μs linac pulses.
methodsA modified clinical linac delivered an electron FLASH beam of >50 Gy/s to clinical isocenter. This modification removed the x-ray target and flattening filter, leading to a beam that was symmetric and gaussian, as verified with GafChromic EBT-XD film. Lateral projected 2D dose distributions for each linac pulse were imaged in a quinine-doped water tank using a gated intensified camera, and an inverse Abel transform reconstruction provided 3D images for on-axis depth dose values. A total of 20 pulses were delivered with a 10 MeV, 1.5 cm circular beam, and beam with jaws wide open (40 × 40 cm
resultsThe R
conclusionsOptical imaging of radioluminescence was presented as a valuable tool for establishing a baseline for the recently initiated electron FLASH beam at our institution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.