Evidence map›Paper›PMID 33730345›Full record

Trial reportWorld journal of pediatrics : WJP2021

Continuous positive airway pressure acutely increases exercise duration in children with severe therapy-resistant asthma: a randomized crossover trial.

Cláudia Silva Schindel, Daniele Schiwe, João Paulo Heinzmann-Filho, Natália Evangelista Campos, Paulo Márcio Pitrez, Márcio Vinícius Fagundes Donadio

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of pediatrics : WJP, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Non-invasive positive pressure ventilation for acute asthma in children.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Cláudia Silva SchindelLaboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Av. Ipiranga, 6690, 2º andar, Porto Alegre, RS, CEP 90610-000, Brazil.
Daniele SchiweLaboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Av. Ipiranga, 6690, 2º andar, Porto Alegre, RS, CEP 90610-000, Brazil.
João Paulo Heinzmann-FilhoLaboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Av. Ipiranga, 6690, 2º andar, Porto Alegre, RS, CEP 90610-000, Brazil.
Natália Evangelista CamposLaboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Av. Ipiranga, 6690, 2º andar, Porto Alegre, RS, CEP 90610-000, Brazil.
Paulo Márcio PitrezHospital Moinhos de Vento, Porto Alegre, Brazil and Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
Márcio Vinícius Fagundes DonadioLaboratory of Pediatric Physical Activity, Centro Infant, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Av. Ipiranga, 6690, 2º andar, Porto Alegre, RS, CEP 90610-000, Brazil. mdonadio@pucrs.br.ORCID http://orcid.org/0000-0001-8836-9109
Pontifícia Universidade Católica do Rio Grande do Sul · BRHospital Moinhos de Vento · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

backgroundLower exercise tolerance is an important component of asthma and the possible effects of non-invasive ventilation on exercise capacity in individuals with severe therapy-resistant asthma (STRA) are unknown. This study aimed to evaluate the immediate effect of continuous positive airway pressure (CPAP) on exercise tolerance in children with STRA.

methodsWe performed a controlled, randomized, crossover clinical trial including subjects aged 6 to 18 years old diagnosed with STRA. Clinical, anthropometric and lung function data were collected. The participants in the intervention group (IG) used CPAP (PEEP 10cmH

resultsThirteen subjects with a mean age of 12.30 ± 1.7 years were included. The variables of peak expiratory flow (PEF) and forced expiratory volume in the first second (FEV

conclusionThe results suggest that the use of CPAP before physical exercise increases exercise duration in children and adolescents with STRA.

Indexed as

Continuous Positive Airway PressureAdolescentAsthmaChildCross-Over StudiesExercise TestExercise ToleranceFemaleHumansMaleRespiratory Function TestsAsthmaExercise-induced bronchospasmExercise testExercise toleranceNon-invasive ventilationOxygen consumption

Identifiers

PMID33730345
OpenAlexW3137556637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.