Evidence map›Paper›PMID 33730315›Full record

ArticleInternational ophthalmology2021

The correct graft orientation during descemet membrane endothelial keratoplasty (DMEK) using the "bubble-tap" technique.

Georgios Perdikakis, Sofia Fili, Iraklis Vastardis, Markus Kohlhaas

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Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Georgios PerdikakisClinic of Ophthalmology, St. Johannes Hospital, Johannesstrasse 9-17, 44137, Dortmund, Germany. dr.perdi@gmail.com.
Sofia FiliClinic of Ophthalmology, St. Johannes Hospital, Johannesstrasse 9-17, 44137, Dortmund, Germany.
Iraklis VastardisClinic of Ophthalmology Pallas, Zurich, Switzerland.
Markus KohlhaasClinic of Ophthalmology, St. Johannes Hospital, Johannesstrasse 9-17, 44137, Dortmund, Germany.
St.-Johannes-Hospital Dortmund · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo demonstrate a novel, alternative endothelium Descemet membrane layer (EDM) orientation method in Descemet membrane endothelial keratoplasty (DMEK) that does not involve prior ink or trepanation marking of the graft, or intraoperative ocular coherence tomography (OCT) guided graft implantation during surgery, thus preventing the occurrence of an upside-down graft implantation that leads with certainty to primary graft failure.

methodsFrom 2017 to early 2020, 500 eyes underwent DMEK operation using the "bubble-tap" technique first described from Dr. Perdikakis in the department of ophthalmology of St.-Johannes- Hospital in Dortmund in Germany. Primary graft failure and re-bubbling results following "bubble-tap" assisted DMEK are presented.

resultsPrimary graft failure due to upside-down graft implantation was not observed in any patient. Re-bubbling was performed in 4.8% of the eyes. In 1.8% of the cases, a re-DMEK was performed due to a graft failure.

conclusionThe "bubble-tap" technique is a novel, reliable and easy to master orientation method of EDM that enables the surgeon to perform DMEK with safety even in complicated cases with poor visibility in the anterior chamber, while it yields superior or equal results in comparison to other graft marking methods or intraoperative OCT-guided graft implantation.

Indexed as

Descemet MembraneDescemet Stripping Endothelial KeratoplastyCell CountEndothelium, CornealGermanyHumansRetrospective StudiesBubble-tap techniqueDMEKUpside down

Identifiers

PMID33730315
OpenAlexW3136443750

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.