ArticlePloS one2021
Geographical and socioeconomic inequalities in female breast cancer incidence and mortality in Iran: A Bayesian spatial analysis of registry data.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Scientometric Analysis of Articles on Spatial Epidemiology of Cancer in Iran: A Systematic Review.Iranian journal of medical sciences · 2023Pooled it
- Breast Cancer Molecular Subtypes and Receptor-Related Risk Factor Associations: A Cross-Sectional Study.Health science reports · 2026Article
- Epidemiological and Clinical Risk Factors for Breast Cancer-Related Lymphedema: A Case-Control Study From Hamadan, Western Iran.BioMed research international · 2026Article
- National and Subnational Burden of Female Breast Cancer in Iran from 2010 to 2021.Diseases (Basel, Switzerland) · 2025Article
- Spatiotemporal Epidemiology of Female Thyroid Cancer: A Retrospective Population-Based Registry Study in the Hamadan Province, Iran (2010-2019).Archives of Iranian medicine · 2025Article
- The estimated incidence of uterine corpus cancers among permanent residents in mainland China using Bayesian spatial modeling.Scientific reports · 2025Article
- Bayesian Spatial Analysis of the Incidence Rate of Patients with Breast Cancer in Southern Iran.Iranian journal of medical sciences · 2025Article
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- Article
- Utilization of a Joint Point Regression Model for Predicting Mortality Rates of Common Cancers in Babol City.Cancer reports (Hoboken, N.J.) · 2025Article
- Targeting hypoxia-inducible factor 1 alpha augments synergistic effects of chemo/immunotherapy via modulating tumor microenvironment in a breast cancer mouse model.BioImpacts : BI · 2025Article
- Breast and Ovarian Cancers' Incidence Trends Among Iraqi Women During 2012-2022 and Their Relationship to Fertility Patterns.Sultan Qaboos University medical journal · 2025Article
- Application of machine learning in breast cancer survival prediction using a multimethod approach.Scientific reports · 2024Article
- Examining the Completeness of Breast Cancer Pathology Reports Registered in the Population-Based Cancer Registration System in Iran during 2016 to 2018.Medical journal of the Islamic Republic of Iran · 2024Article
- Biomarker discovery and development of prognostic prediction model using metabolomic panel in breast cancer patients: a hybrid methodology integrating machine learning and explainable artificial intelligence.Frontiers in molecular biosciences · 2024Article
- System biology mediated assessment of molecular mechanism for sinapic acid against breast cancer: via network pharmacology and molecular dynamic simulation.Scientific reports · 2023Article
- National and subnational burden of female and male breast cancer and risk factors in Iran from 1990 to 2019: results from the Global Burden of Disease study 2019.Breast cancer research : BCR · 2023Article
- Expansion of the quality of care index on breast cancer and its risk factors using the global burden of disease study 2019.Cancer medicine · 2023Article
- Factors related to clinical breast examination: A cross-sectional study.Journal of family medicine and primary care · 2022Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Iran, trends in breast cancer incidence and mortality have generally been monitored at national level. The purpose of this study is to examine province-level disparities in age-standardised breast cancer incidence versus mortality from 2000 to 2010 and their association with socioeconomic status.
methodsIn this study, data from Iran's national cancer and death registry systems, and covariates from census and household expenditure surveys were used. We estimated the age-standardised incidence and mortality rates in women aged more than 30 years for all 31 provinces in the consecutive time intervals 2000-2003, 2004-2007 and 2008-2010 using a Bayesian spatial model.
resultsMean age-standardised breast cancer incidence across provinces increased over time from 15.0 per 100,000 people (95% credible interval 12.0,18.3) in 2000-2003 to 39.6 (34.5,45.1) in 2008-2010. The mean breast cancer mortality rate declined from 10.9 (8.3,13.8) to 9.9 (7.5,12.5) deaths per 100,000 people in the same period. When grouped by wealth index quintiles, provinces in the highest quintile had higher levels of incidence and mortality. In the wealthiest quintile, reductions in mortality over time were larger than those observed among provinces in the poorest quintile. Relative breast cancer mortality decreased by 16.7% in the highest quintile compared to 10.8% in the lowest quintile.
conclusionsBreast cancer incidence has increased over time, with lower incidence in the poorest provinces likely driven by underdiagnoses or late-stage diagnosis. Although the reported mortality rate is still higher in wealthier provinces, the larger decline over time in these provinces indicates a possible future reversal, with the most deprived provinces having higher mortality rates. Ongoing analysis of incidence and mortality at sub-national level is crucial in addressing inequalities in healthcare systems and public health both in Iran and elsewhere.
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