Evidence map›Paper›PMID 33730020›Full record

ArticlePloS one2021

A novel quantitative analysis method for idiopathic epiretinal membrane.

Davide Allegrini, Giovanni Montesano, Stefania Marconi, Nicoletta Rosso, Giovanni Ometto, Raffaele Raimondi, Ferdinando Auricchio, Panagiotis Tsoutsanis, Francesco Semeraro, Matteo Cacciatori and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Davide AllegriniDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Giovanni MontesanoCity, University of London-Optometry and Visual Sciences, London, United Kingdom.
Stefania MarconiDepartment of Civil Engineering and Architecture, University of Pavia, Pavia, Italy.
Nicoletta RossoOphthalmology Service, Istituti Ospitalieri di Cremona, Cremona, Italy.
Giovanni OmettoCity, University of London-Optometry and Visual Sciences, London, United Kingdom.
Raffaele RaimondiDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.ORCID 0000-0001-8472-7984
Ferdinando AuricchioDepartment of Civil Engineering and Architecture, University of Pavia, Pavia, Italy.
Panagiotis TsoutsanisDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Francesco SemeraroDepartment of Medical and Surgical Specialties, Radiological Sciences and Public Health, Eye Clinic, University of Brescia, Brescia, Italy.
Matteo CacciatoriOphthalmology Service, Istituti Ospitalieri di Cremona, Cremona, Italy.
David P CrabbCity, University of London-Optometry and Visual Sciences, London, United Kingdom.
Mario R RomanoDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Humanitas University · ITIstituti Ospitalieri di Cremona · ITMoorfields Eye Hospital NHS Foundation Trust · GBUniversity of Pavia · ITCity, University of London · GBUniversity of Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole.

methodsRetrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measures the shift in position of vascular crossings after surgery from a fixed point, which is the retinal pigmented epithelium. This shift is defined as the relaxation index (RI) and represents a measure of the postoperative movement of the retina due to released traction after surgery.

resultsBest-corrected visual acuity was significantly better than baseline at all follow ups while the RI had its maximum value at baseline. Moreover, we found a significant correlation between best-corrected visual acuity at 6 months and RI at baseline.

conclusionWhile all previous published methods focused on bi-dimensional changes observed in a small region, this study introduces a three-dimensional assessment of tractional forces. Future integration of RI into built-in processing software will allow systematic three-dimensional measurement of intraretinal traction.

Indexed as

AgedEpiretinal MembraneEvaluation Studies as TopicFemaleHumansMaleRetinaRetinal Pigment EpitheliumRetrospective StudiesTomography, Optical CoherenceVisual AcuityVitrectomy

Identifiers

PMID33730020
PMCPMC7968655
OpenAlexW3136276629

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.