Evidence map›Paper›PMID 33729912›Full record

ArticleeLife2021

A conserved cell division protein directly regulates FtsZ dynamics in filamentous and unicellular actinobacteria.

Félix Ramos-León, Matthew J Bush, Joseph W Sallmen, Govind Chandra, Jake Richardson, Kim C Findlay, Joseph R McCormick, Susan Schlimpert

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Morphology-engineered alleviation of mycelial aggregation inSynthetic and systems biotechnology · 2025
    Article
  4. Article
  5. How do spherical bacteria regulate cell division?Biochemical Society transactions · 2025
    Review
  6. Microbe Profile:Microbiology (Reading, England) · 2025
    Review
  7. Article
  8. Tip extension and simultaneous multiple fission in a filamentous bacterium.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. MipZ caps the plus-end of FtsZ polymers to promote their rapid disassembly.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Félix Ramos-León *Department of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom.
Matthew J Bush *Department of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom.ORCID 0000-0001-8216-0152
Joseph W SallmenDepartment of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom.
Govind ChandraDepartment of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom.ORCID 0000-0002-7882-6676
Jake RichardsonDepartment of Cell and Developmental Biology, John Innes Centre, Norwich, United Kingdom.
Kim C FindlayDepartment of Cell and Developmental Biology, John Innes Centre, Norwich, United Kingdom.
Joseph R McCormickDepartment of Biological Sciences, Duquesne University, Pittsburgh, United States.ORCID 0000-0002-9071-7296
Susan SchlimpertDepartment of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom.ORCID 0000-0001-6364-8056
John Innes Centre · GBDuquesne University · US

Funding

CHROMOSOME SEGREGATION IN A FILAMENTOUS BACTERIUMR15GM096268 · NIGMS · DUQUESNE UNIVERSITY · PI MC CORMICK, JOSEPH R · 2011 to 2011
$269k
Biotechnology and Biological Sciences Research Council BBS/E/J/000PR9791Biotechnology and Biological Sciences Research Council BB/T015349/1NIGMS NIH HHS R15 GM096268NIH HHS GM096268
6 · The paper itself

Abstract

Bacterial cell division is driven by the polymerization of the GTPase FtsZ into a contractile structure, the so-called Z-ring. This essential process involves proteins that modulate FtsZ dynamics and hence the overall Z-ring architecture. Actinobacteria like

Indexed as

Bacterial ProteinsCell DivisionCytoskeletal ProteinsMycobacterium smegmatisStreptomycesBacterial ProteinsCytoskeletal ProteinsFtsZ protein, Bacteriacell divisionFtsZinfectious diseasemicrobiologyMycobacterium smegmatisprokaryotic developmentsporulationStreptomyces venezuelae

Identifiers

PMID33729912
PMCPMC7968930
OpenAlexW3136670477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.