Evidence map›Paper›PMID 33729834›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2021

Liver injury after small bowel resection is prevented in obesity-resistant 129S1/SvImJ mice.

Emily J Onufer, Yong-Hyun Han, Cathleen Courtney, Allie Steinberger, Maria Tecos, Stephanie Sutton, Anne Sescleifer, Jocelyn Ou, Rafael Sanguinetti Czepielewski, Gwendalyn J Randolph and 1 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. An American Physiological Society cross-journal Call for Papers on "The Physiology of Obesity".American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  4. A novel maladaptive unfolded protein response as a mechanism for small bowel resection-induced liver injury.American journal of physiology. Gastrointestinal and liver physiology · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Emily J OnuferDivision of Pediatric Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.ORCID 0000-0002-8802-5346
Yong-Hyun HanLaboratory of Pathology and Physiology, College of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Cathleen CourtneyDivision of Pediatric Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Allie SteinbergerDivision of Pediatric Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Maria TecosDivision of Pediatric Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Stephanie SuttonDivision of Pediatric Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Anne SescleiferDivision of Pediatric Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Jocelyn OuDivision of Pediatric Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Rafael Sanguinetti CzepielewskiDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri.
Gwendalyn J RandolphDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri.
Brad W WarnerDivision of Pediatric Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Washington University in St. Louis · USKangwon National University · KR

Funding

Washington University DDRCC Supplemental Equipment RequestP30DK052574 · NIDDK · WASHINGTON UNIVERSITY · PI Nicholas O. Davidson · 2000 to 2026
$30.8M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI James Alexander Fitzpatrick · 2013 to 2026
$27.1M
TRAINING PROGRAM IN IMMUNOLOGY AND IMMUNOGENETICST32AI007163 · NIAID · WASHINGTON UNIVERSITY · PI Kenneth M Murphy, Kodi S Ravichandran · 1985 to 2026
$14.8M
Pediatric Gastroenterology Research Training ProgramT32DK077653 · NIDDK · WASHINGTON UNIVERSITY · PI PHILLIP I TARR · 2007 to 2026
$5.8M
DIFFERENTIATION AND FUNCTION OF MONOCYTES AND MACROPHAGESR37AI049653 · NIAID · WASHINGTON UNIVERSITY · PI RANDOLPH, GWENDALYN J · 2016 to 2025
$4.3M
INTEGRATING CELL & LIPOPROTEIN TRAFFICKING WITH VASCULAR BIOLOGY IN HUMAN IBDDP1DK109668 · NIDDK · WASHINGTON UNIVERSITY · PI RANDOLPH, GWENDALYN J · 2015 to 2019
$3.8M
NIAID NIH HHS R37 AI049653NIAID NIH HHS T32 AI007163NIDDK NIH HHS DP1 DK109668NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK052574NIDDK NIH HHS P30 DK056341NIDDK NIH HHS T32 DK077653
6 · The paper itself

Abstract

Intestinal failure-associated liver disease is a major morbidity associated with short bowel syndrome. We sought to determine if the obesity-resistant mouse strain (129S1/SvImJ) conferred protection from liver injury after small bowel resection (SBR). Using a parenteral nutrition-independent model of resection-associated liver injury, C57BL/6J and 129S1/SvImJ mice underwent a 50% proximal SBR or sham operation. At postoperative

Indexed as

Adipose Tissue, WhiteAnimalsBiomarkersDigestive System Surgical ProceduresDisease Models, AnimalEndotoxinsFatty Acids, NonesterifiedIntestine, SmallLipidsLiverLiver CirrhosisLiver DiseasesMiceMice, Inbred C57BLObesityShort Bowel SyndromeBiomarkersEndotoxinsFatty Acids, NonesterifiedLipidsTriglyceridesintestinal failure-associated liver diseaseshort bowel syndromesmall bowel resection

Identifiers

PMID33729834
PMCPMC8202193
OpenAlexW3136806692

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.