Evidence map›Paper›PMID 33729420›Full record

SynthesisSao Paulo medical journal = Revista paulista de medicina

Prediction of all-cause and cardiovascular mortality using central hemodynamic indices among elderly people: systematic review and meta-analysis.

Tarsila Vieceli, Bárbara Brambilla, Raphael Quintana Pereira, Bruno Schmidt Dellamea, Airton Tetelbom Stein, Guilherme Brasil Grezzana

Open access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Sao Paulo medical journal = Revista paulista de medicina. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Tarsila VieceliMD, MSc. Internal Medicine Resident, Hospital de Clínicas de Porto Alegre, Porto Alegre (RS), Brazil.ORCID http://orcid.org/0000-0001-6274-1320
Bárbara BrambillaMedical Student, Universidade de Caxias do Sul (UCS), Caxias do Sul (RS), Brazil.ORCID http://orcid.org/0000-0003-4993-4122
Raphael Quintana PereiraMD. Cardiovascular Surgeon, Hospital Infantil Dr. Jeser Amarante Faria, Joinville (SC), Brazil.ORCID http://orcid.org/0000-0002-9167-2210
Bruno Schmidt DellameaMD, PhD. Professor, Universidade de Caxias do Sul (UCS), Caxias do Sul (RS), Brazil.ORCID http://orcid.org/0000-0003-1069-4731
Airton Tetelbom SteinMD, PhD. Professor, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre (RS), Brazil.ORCID http://orcid.org/0000-0002-8756-8699
Guilherme Brasil GrezzanaMD, PhD. Cardiologist, Clínica Del Cuore, Antônio Prado (RS), Brazil.ORCID http://orcid.org/0000-0003-1310-9075
Universidade de Caxias do Sul · BRHospital de Clínicas de Porto Alegre · BRHospital Infantil Albert Sabin · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite widespread usage of central blood pressure assessment its predictive value among elderly people remains unclear.

objectiveTo ascertain the capacity of central hemodynamic indices for predicting future all-cause and cardiovascular hard outcomes among elderly people. DESIGN AND

settingSystematic review and meta-analysis developed at the Del Cuore cardiology clinic, in Antonio Prado, Rio Grande do Sul, Brazil.

methods312 full-text articles were analyzed, from which 35 studies were included for systematic review. The studies included needed to report at least one central hemodynamic index among patients aged 60 years or over.

resultsFor all-cause mortality, aortic pulse wave velocity (aPWV) and central systolic blood pressure (SBP) were significant, respectively with standardized mean difference (SMD) 0.85 (95% confidence interval, CI 0.69-1.01; I2 96%; P < 0.001); and SMD 0.27 (95% CI 0.15-0.39; I2 77%; P 0.012). For cardiovascular mortality brachial-ankle PWV (baPWV), central SBP and carotid-femoral PWV (cfPWV) were significant, respectively SMD 0.67 (95% CI 0.40-0.93; I2 0%; P 0.610); SMD 0.65 (95% CI 0.48- 0.82; I2 80%; P 0.023); and SMD 0.51 (95% CI 0.32-0.69; I2 85%; P 0.010).

conclusionsThe meta-analysis results showed that aPWV was promising for predicting all-cause mortality, while baPWV and central SBP demonstrated consistent results in evaluating cardiovascular mortality outcomes. Thus, the findings support usage of central blood pressure as a risk predictor for hard outcomes among elderly people. REGISTRATION NUMBER IN PROSPERO: RD42018085264.

Indexed as

Cardiovascular DiseasesPulse Wave AnalysisAgedBlood PressureBrachial ArteryBrazilHumansMiddle Aged

Identifiers

PMID33729420
PMCPMC9632515
OpenAlexW3137561638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.