Evidence map›Paper›PMID 33729285›Full record

ArticleEinstein (Sao Paulo, Brazil)2021

Medication regimen complexity of coronary artery disease patients.

Marlon Silva Tinoco, Ronara Camila de Souza Groia-Veloso, Jéssica Nathália Domingos Dos Santos, Maria Gabriela Martins Cruzeiro, Bianca Menezes Dias, Adriano Max Moreira Reis

Open access · diamondAbstract read
In one paragraph

Article in Einstein (Sao Paulo, Brazil), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marlon Silva TinocoHospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID http://orcid.org/0000-0002-5658-4434
Ronara Camila de Souza Groia-VelosoHospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID http://orcid.org/0000-0001-8704-4126
Jéssica Nathália Domingos Dos SantosHospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID http://orcid.org/0000-0001-8195-7055
Maria Gabriela Martins CruzeiroFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID http://orcid.org/0000-0002-8114-3999
Bianca Menezes DiasHospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID http://orcid.org/0000-0002-8842-3643
Adriano Max Moreira ReisFaculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID http://orcid.org/0000-0002-0017-7338
Hospital das Clínicas da Universidade Federal de Minas Gerais · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the factors associated with the high complexity of medication regimen in patients with coronary artery disease.

methodsA cross-sectional study was carried out in a multiprofessional cardiology outpatient clinic, in the Secondary Care of the Unified Health System, where sociodemographic (age, sex, and education), clinical (number of health conditions, cardiovascular diagnoses, and comorbidities) and pharmacotherapeutic (adherence, polypharmacy, and cardiovascular polypharmacy) characteristics were collected. These were related to complexity of medication regimen, measured through the medication regimen complexity index. The classification of high complexity of medication regimen was carried out using standardization for the older adults and stratification for adult patients, as suggested in the literature.

resultsThe total complexity medication regimen of 148 patients had a median of 17.0 (interquartile range of 10.5). In the univariate analysis, the factors associated with high complexity were heart failure, diabetes mellitus, hypertension, five or more diseases, and non-adherence to treatment. In the final model, after logistic regression, there was a statistically significant association (p<0.05) with the variables diabetes mellitus, hypertension, and non-adherence.

conclusionThe high complexity of medication regimen in patients with coronary artery disease was associated with the presence of diabetes mellitus, hypertension, and reports of non-adherence to treatment.

Indexed as

Coronary Artery DiseaseMedication AdherencePolypharmacyComorbidityCross-Sectional StudiesDiabetes MellitusHumansHypertensionLogistic Models

Identifiers

PMID33729285
PMCPMC7935084
OpenAlexW3135306280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.