Evidence map›Paper›PMID 33729017›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2021

Electrically induced quadriceps fatigue in the contralateral leg impairs ipsilateral knee extensors performance.

Fabio Giuseppe Laginestra, Markus Amann, Emine Kirmizi, Gaia Giuriato, Chiara Barbi, Federico Ruzzante, Anna Pedrinolla, Camilla Martignon, Cantor Tarperi, Federico Schena and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 3 countries.

Fabio Giuseppe LaginestraDepartment of Neurosciences, Biomedicine, and Movement, University of Verona, Verona, Italy.
Markus AmannDepartment of Anaesthesiology, University of Utah, Salt Lake City, Utah.
Emine KirmiziDepartment of Neurosciences, Biomedicine, and Movement, University of Verona, Verona, Italy.
Gaia GiuriatoDepartment of Neurosciences, Biomedicine, and Movement, University of Verona, Verona, Italy.
Chiara BarbiDepartment of Neurosciences, Biomedicine, and Movement, University of Verona, Verona, Italy.
Federico RuzzanteDepartment of Neurosciences, Biomedicine, and Movement, University of Verona, Verona, Italy.
Anna PedrinollaDepartment of Neurosciences, Biomedicine, and Movement, University of Verona, Verona, Italy.
Camilla MartignonDepartment of Neurosciences, Biomedicine, and Movement, University of Verona, Verona, Italy.
Cantor TarperiDepartment of Neurosciences, Biomedicine, and Movement, University of Verona, Verona, Italy.
Federico SchenaDepartment of Neurosciences, Biomedicine, and Movement, University of Verona, Verona, Italy.
Massimo VenturelliDepartment of Neurosciences, Biomedicine, and Movement, University of Verona, Verona, Italy.
University of Verona · ITUniversity of Utah · US

Funding

Role of Sensory Neurons in Human Cardiovascular DiseaseR01HL116579 · NHLBI · UNIVERSITY OF UTAH · PI AMANN, MARKUS · 2013 to 2021
$3.4M
Cardiovasomobility Research Training ProgramT32HL139451 · NHLBI · UNIVERSITY OF UTAH · PI SUPIANO, MARK A, WRAY, D. WALTER · 2018 to 2022
$1.4M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL-139451NHLBI NIH HHS R01 HL116579RRD VA I01 RX003343
6 · The paper itself

Abstract

Muscle fatigue induced by voluntary exercise, which requires central motor drive, causes central fatigue that impairs endurance performance of a different, nonfatigued muscle. This study investigated the impact of quadriceps fatigue induced by electrically induced (no central motor drive) contractions on single-leg knee-extension (KE) performance of the subsequently exercising ipsilateral quadriceps. On two separate occasions, eight males completed constant-load (85% of maximal power-output) KE exercise to exhaustion. In a counterbalanced manner, subjects performed the KE exercise with no pre-existing quadriceps fatigue in the contralateral leg on one day (No-PreF), whereas on the other day, the same KE exercise was repeated following electrically induced quadriceps fatigue in the contralateral leg (PreF). Quadriceps fatigue was assessed by evaluating pre- to postexercise changes in potentiated twitch force (ΔQ

Indexed as

AdultElectromyographyExerciseHumansKneeKnee JointLegMaleMuscle ContractionMuscle FatigueMuscle, SkeletalQuadriceps Musclecentral commandelectrical stimulationgroup III and IV afferentsmuscle fatigue

Identifiers

PMID33729017
PMCPMC8163605
OpenAlexW3138819567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.