Evidence map›Paper›PMID 33728898›Full record

ArticleACS infectious diseases2021

Recombinant Human Secretory IgA Induces

Angelene F Richards, Danielle E Baranova, Matteo S Pizzuto, Stefano Jaconi, Graham G Willsey, Fernando J Torres-Velez, Jennifer E Doering, Fabio Benigni, Davide Corti, Nicholas J Mantis

Open access · hybridAbstract read
In one paragraph

Article in ACS infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. A systems pharmacology-basedFrontiers in veterinary science · 2026
    Article
  4. Article
  5. AInfection and immunity · 2025
    Article
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  11. Review
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  17. Article
  18. Reduced immunogenicity of a liveFrontiers in immunology · 2023
    Article
  19. Gut microbiome and breast-feeding: Implications for early immune development.The Journal of allergy and clinical immunology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Angelene F RichardsDepartment of Biomedical Sciences, University at Albany School of Public Health, Albany, New York 12208, United States.
Danielle E BaranovaDivision of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, New York 12208, United States.
Matteo S PizzutoHumabs BioMed SA a Subsidiary of Vir Biotechnology Inc., 6500 Bellinzona, Switzerland.
Stefano JaconiHumabs BioMed SA a Subsidiary of Vir Biotechnology Inc., 6500 Bellinzona, Switzerland.
Graham G WillseyDivision of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, New York 12208, United States.
Fernando J Torres-VelezDivision of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, New York 12208, United States.
Jennifer E DoeringDivision of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, New York 12208, United States.
Fabio BenigniHumabs BioMed SA a Subsidiary of Vir Biotechnology Inc., 6500 Bellinzona, Switzerland.
Davide CortiHumabs BioMed SA a Subsidiary of Vir Biotechnology Inc., 6500 Bellinzona, Switzerland.
Nicholas J MantisDepartment of Biomedical Sciences, University at Albany School of Public Health, Albany, New York 12208, United States.ORCID 0000-0002-5083-8640
New York State Department of Health · USVir Biotechnology (Switzerland) · CH

Funding

Mechanisms of IgA-mediated immunity to SalmonellaR03AI119647 · NIAID · WADSWORTH CENTER · PI MANTIS, NICHOLAS J. · 2015 to 2016
$145k
NIAID NIH HHS R03 AI119647
6 · The paper itself

Abstract

As the predominant antibody type in mucosal secretions, human colostrum, and breast milk, secretory IgA (SIgA) plays a central role in safeguarding the intestinal epithelium of newborns from invasive enteric pathogens like the Gram-negative bacterium

Indexed as

Immunoglobulin A, SecretorySalmonella typhimuriumAgglutinationHumansImmunity, MucosalImmunoglobulin AInfant, NewbornIntestinal MucosaLymphoid TissueImmunoglobulin AImmunoglobulin A, SecretoryantibodyimmunityPeyer’s patchSalmonella entericasecretory immunoglobulin A

Identifiers

PMID33728898
PMCPMC8154420
OpenAlexW3138793622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.