ArticleJournal of cancer education : the official journal of the American Association for Cancer Education2022
African American Cancer Survivors' Perspectives on Cancer Clinical Trial Participation in a Safety-Net Hospital: Considering the Role of the Social Determinants of Health.
Article in Journal of cancer education : the official journal of the American Association for Cancer Education, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Pooled it
- Recruitment and retention strategies for improving representation in clinical research: A meta-synthesis.PloS one · 2025Pooled it
- Pooled it
- Exploring Racial Disparities in Awareness and Perceptions of Oncology Clinical Trials: Cross-Sectional Analysis of Baseline Data From the mychoice Study.JMIR cancer · 2024Trial
- Patient and Caregiver Reported Barriers to Cancer Clinical Trial Participation: A Scoping Review.Cancer reports (Hoboken, N.J.) · 2026Article
- Perspectives on GUIDE (Guiding participation toward understanding, inclusion, diversity, and equity for cancer trials): a clinical trial access intervention.Cancer causes & control : CCC · 2026Article
- Patient perspective of Hesitancies and strategies to increase cancer clinical trial participation.Journal of clinical and translational science · 2026Article
- Perspectives of African American couples regarding participation in trials of treatments for obstructive sleep apnea.Journal of the National Medical Association · 2025Article
- Understanding Inclusion and Participation of People From Black African Diaspora Communities in Health and Care Research: A Realist Review.Health expectations : an international journal of public participation in health care and health policy · 2025Review
- Barriers to recruitment of an observational SARS-CoV-2 emergency department cohort at Boston Medical Center.BMC emergency medicine · 2025Observational
- A pilot randomized controlled study of integrated kidney palliative care and chronic kidney disease care implemented in a safety-net hospital: Protocol for a pilot study of feasibility of a randomized controlled trial.Contemporary clinical trials communications · 2025Article
- The Importance of Including Underserved Populations in Research.Pharmaceutical medicine · 2025Review
- Racial Differences in ctDNA Profiles, Targeted Therapy Use, and Outcomes in Metastatic Breast Cancer.JAMA network open · 2025Article
- Cancer clinical trial participation: a qualitative study of Black/African American communities' and patient/survivors' recommendations.JNCI cancer spectrum · 2025Article
- Breast cancer clinical trial participation among diverse patients at a comprehensive cancer center.NPJ breast cancer · 2024Article
- Increasing Clinical Trial Participation of Black Women Diagnosed with Breast Cancer.Journal of racial and ethnic health disparities · 2024Article
- Article
- Evaluating Demographic Representation in Clinical Trials: Use of the Adaptive Coronavirus Disease 2019 Treatment Trial (ACTT) as a Test Case.Open forum infectious diseases · 2023Article
- Linking social and built environmental factors to leisure-time physical activity in rural cancer survivors.Journal of the National Cancer Institute. Monographs · 2023Article
- Disparities in awareness of and willingness to participate in cancer clinical trials between African American and White cancer survivors.BMC cancer · 2022Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
Although there has been an increase focus on recruitment of minority populations at safety-net hospitals into cancer clinical trials, there is still a paucity of research exploring minority participation in cancer clinical trials at safety-net settings. The study utilized a multi-level, qualitative approach to assess the clinical and non-clinical facilitators and barriers to African American participation in cancer clinical trials at a safety-net hospital. From June 2018 to July 2019, cancer survivors (n = 25) were recruited from a cancer center at a safety-net hospital in the southeastern USA and participated in a 60-min focus group. Data was coded and analyzed to identify the most prominent themes. Most participants were female (78%), with a mean age of 56 years. The majority were diagnosed with breast cancer (68%) and disabled or unemployed (55%). Major themes identified were (1) lack of understanding of cancer clinical trials, (2) perceptions and fears of cancer clinical trials, and (3) preferred role and characteristics of patient navigator. The barriers and facilitators to enrollment in cancer clinical trials were more pronounced in the safety-net setting, given the overdue burden of social determinants of health. Study findings yield important insights and essential practices for recruiting and engaging underrepresented Black cancer patients into cancer clinical trials, specifically for safety-net settings. Including patient navigators may help traverse potential barriers to cancer clinical trial participation and will allow for the attention to social determinants of health, and ultimately increase the number of African Americans participating in cancer clinical trials.
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