ArticleJournal of cancer survivorship : research and practice2022
Self-perceived cognitive functioning and quality of life among cancer survivors: results from the PROFILES registry.
Article in Journal of cancer survivorship : research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Effect of exercise interventions on cognitive function in breast cancer patients and survivors: a systematic review with meta-analysis.Breast cancer (Tokyo, Japan) · 2025Pooled it
- Donepezil for cancer-related cognitive impairment: systematic review and meta-analysis.Clinical and experimental medicine · 2025Pooled it
- Moderators of exercise effects on self-reported cognitive functioning in cancer survivors: an individual participant data meta-analysis.Journal of cancer survivorship : research and practice · 2024Pooled it
- Associations between MoCA screening-positive cognitive impairment, anxiety, depression, and quality of life in patients with oral cancer: a cross-sectional study in China.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Network analysis of head and neck symptoms and fear of cancer recurrence in postoperative laryngeal cancer patients: simulation-based intervention modeling.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Agreement between the EQ-5D-5L anxiety/depression dimension and GAD-7/PHQ-9 for psychological distress assessment in patients with hematologic malignancies.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Patient-reported outcomes in cancer survivorship: insights from two decades of population-based PROFILES registry research.Journal of cancer survivorship : research and practice · 2026Review
- The course of self-perceived cognitive functioning among patients with lymphoma and the co-occurrence with fatigue and psychological distress.Journal of cancer survivorship : research and practice · 2025Article
- Impact of menopausal status on cognitive function in female papillary thyroid carcinoma patients: a longitudinal propensity score matched study.BMC women's health · 2024Article
- Cognitive Symptoms Across Diverse Cancers.JAMA network open · 2024Article
- Observation of changes in quality of life for 5 years after thyroid surgery: an observational cross-sectional study in Korean population.Annals of surgical treatment and research · 2023Article
- Measuring Clinical, Biological, and Behavioral Variables to Elucidate Trajectories of Patient-Reported Outcomes: The PROFILES Registry.Journal of the National Cancer Institute · 2022Article
- Anxiety and quality of life among papillary thyroid cancer patients awaiting final pathology results after surgery.Endocrine · 2022Article
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Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim was to investigate the level of self-perceived cognitive functioning and its associated factors among a large population-based cohort of cancer survivors and their matched controls.
methodsData were obtained from population-based PROFILES registry cohorts, including colon, rectum, prostate or thyroid cancer, Hodgkin lymphoma (HL), non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia, multiple myeloma (MM), melanoma, or basal cell carcinoma (BCC)/squamous cell carcinoma (SCC). All patients completed the EORTC QLQ-C30 from which self-perceived cognitive functioning, fatigue, functioning, and global health status/quality of life (GHS/QoL) were used. The PROFILES registry data were linked with the Netherlands Cancer Registry to obtain sociodemographic and clinical data.
resultsSix thousand seven hundred eighty-six survivors were included (response rate=76%). Survivors, except for melanoma and BCC/SCC, reported on average lower self-perceived cognitive functioning scores compared to their matched controls (all p's<0.01). Largest differences with the norm were observed in thyroid cancer, HL, NHL and MM, and younger survivors (<50 years). Survivors with lower emotional functioning and more fatigue were more likely to report impaired self-perceived cognitive functioning.
conclusionSelf-perceived impaired cognitive functioning is prevalent among a wide range of cancer survivors, especially among survivors <50 years. Approaches targeting cognitive problems including attention for co-occurring symptoms such as fatigue and emotional impairments are needed to improve care for these patients. IMPLICATIONS FOR CANCER SURVIVORS: Cancer survivors and clinicians should be aware that impaired self-perceived cognitive functioning is a frequently reported consequence of cancer and its treatment among survivors of various cancer types. Clinicians can redirect survivors to a relevant healthcare provider or program to target cognitive problems.
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