Evidence map›Paper›PMID 33728570›Full record

SynthesisTechniques in coloproctology2021

A mapping review of sacrococcygeal pilonidal sinus disease.

M Kumar, W H Clay, M J Lee, S R Brown, D Hind

Registry-linked trialOpen access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Techniques in coloproctology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05474911 (RANDOMIZED COMPARATIVE CLINICAL STUDY BETWEEN TWO TREATMENT STRATEGIES IN PATIENTS WITH PILONIDAL SINUS), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05474911 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Randomized comparative clinical study between two treatment strategies in patients with pilonidal sinus: conventional care versus negative pressure therapy.

TypeinterventionalSponsorSebastiano BiondoRan2022 to 2023Enrolled94ConditionsPilonidal Sinus, Wound HealArmsNegative pressure therapy, Conventional wound care
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Review
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Research and practice priorities in pilonidal sinus disease: a consensus from the PITSTOP study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024
    Article
  10. Article
  11. Pilonidal sinus disease: a brief guide for primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

M KumarThe Medical School, University of Sheffield, Sheffield, UK.
W H ClayAcademic Directorate of General Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
M J LeeAcademic Directorate of General Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK. M.j.lee@sheffield.ac.uk.ORCID 0000-0001-9971-1635
S R BrownAcademic Directorate of General Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
D HindClinical Trials Research Unit, School of Health and Related Research, University of Sheffield, Sheffield, UK.
Sheffield Teaching Hospitals NHS Foundation Trust · GBUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPilonidal sinus is a hole in the natal cleft which may cause severe pain and become infected. The evidence base for management of pilonidal sinus is said to be poor quality, poorly focused and rapidly proliferating. We undertook a systematic mapping review to provide a broad overview of the field and support the identification of research priorities.

methodsWe searched MEDLINE, CINAHL, and EMBASE from inception to 22nd Nov 2020 for primary research studies focused on the management of pilonidal sinus. We extracted data on study design and categorised studies under five major headings ('non-surgical treatment', 'surgical treatment', 'aftercare' and 'other'), producing frequency counts for different study designs. Gaps in research were identified from published systematic reviews and tabulated.

resultsWe identified 983 eligible studies, of which 36 were systematic reviews and/or meta-analyses; 121 were randomised controlled trials), and 826 observational studies of various design. The majority of studies evaluated surgical techniques (n = 665), or adjuvant medical interventions (n = 98). The literature on wound care has developed most recently, and the evidence base includes 30% randomised controlled trials. Gaps analysis highlighted comparison of surgical techniques including flaps, laser depilation, and wound care interventions as potential areas for randomised controlled trials.

conclusionsThis mapping review summarises eight decades of research on the management of pilonidal sinus. Further research is needed to identify front-running interventions, understand variation in practice and patient values, and to prioritise future research.

Indexed as

Hair RemovalPilonidal SinusSkin DiseasesHumansSurgical FlapsWound HealingMapping reviewPilonidal sinusSurgerySystematic mapWound care

Identifiers

PMID33728570
PMCPMC8124060
OpenAlexW3136123335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.