Evidence map›Paper›PMID 33728493›Full record

ArticleInternational journal of implant dentistry2021

Laser microgrooved vs. machined healing abutment disconnection/reconnection: a comparative clinical, radiographical and biochemical study with split-mouth design.

Renzo Guarnieri, Gabriele Miccoli, Rodolfo Reda, Alessandro Mazzoni, Dario Di Nardo, Luca Testarelli

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In one paragraph

Article in International journal of implant dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04415801 (Effect of Repeated Removal and Re-placement of Laser Microgrooved and Machined Abutments on Proinflammatory Cytokine Levels Around Dental Implants), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04415801 naunknown statusnot on this map

Effect of Repeated Removal and Re-placement of Laser Microgrooved and Machined Abutments on Proinflammatory Cytokine Levels Around Dental Implants

TypeinterventionalSponsorUniversity of Roma La SapienzaRan2020 to 2020Enrolled20ConditionsPeri-implant MucositisArmsRepeated removal and re-placement of healing and prosthetic abutments
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Renzo GuarnieriDepartment of Oral and Maxillo-Facial Sciences, La Sapienza University of Rome, Rome, Italy. renzoguarnieri@gmail.com.ORCID 0000-0003-1449-8340
Gabriele MiccoliDepartment of Oral and Maxillo-Facial Sciences, La Sapienza University of Rome, Rome, Italy.
Rodolfo RedaDepartment of Oral and Maxillo-Facial Sciences, La Sapienza University of Rome, Rome, Italy.
Alessandro MazzoniDepartment of Oral and Maxillo-Facial Sciences, La Sapienza University of Rome, Rome, Italy.
Dario Di NardoDepartment of Oral and Maxillo-Facial Sciences, La Sapienza University of Rome, Rome, Italy.
Luca TestarelliDepartment of Oral and Maxillo-Facial Sciences, La Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRepeated removal and replacement of healing abutments result in frequent injuries to the soft tissues. PURPOSE: The purpose of this study was to evaluate the effect of disconnection/reconnection of laser microgrooved vs. machined healing and prosthetic abutments on clinical periodontal parameters, marginal bone levels, and proinflammatory cytokine levels around dental implants. MATERIAL AND

methodsTwenty-four patients each received 2 implants with one-stage protocol in a split-mouth design on the same jaw. In each patient, one healing and prosthetic abutments with a laser microgrooved surface (LMS group) and one healing and prosthetic abutments with machined surface (MS group) were used. Four months following implant placement (T0), the healing abutments were disconnnected and reconnected three times to carry out the impression procedures and metal framework try-in. Four weeks later (T1), definitive prosthetic abutments were installated with screw-retained crowns. Modified plaque index (mPI), modified gingival index (mGI) bleeding on probing (BOP), and probing depth (PD) were recorded at T0 and T1. At the same time points, samples for immunological analyses were taken from the sulcus around each implant. Peri-implant crevicular fluid (PICF) samples were analyzed for interleukin-1beta (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor (TNF)-α levels using the ELISA kit.

resultsAt T0 and T1, mPI and mGI showed no statistical difference between the two groups, while higher PD and BoP values were noted for the MS group (P < 0.05). The mean PICF volume and mean concentrations of IL-1β, IL-6, and (TNF)-α in the LMS group were statistically less than those in the MS group (P < 0.05). In addition, comparison of IL-6 and IL-1β mean concentrations at T0 and T1 in the MS group showed a statistically significant increase (p < 0.05) over time, which was not noted for the LMS.

conclusionDisconnection/reconnection of healing and prosthetic abutments with a laser-microgrooved surface resulted in less inflammatory molecular response compared with conventional machined ones.

trial registrationClinicalTrials.gov NCT04415801 , registered 03/06/2020.

Indexed as

Dental ImplantsCrownsHumansLasersMouthRadiographyDental ImplantsAbutmentsCytokinesInflammationPeri-implant crevicular fluid

Identifiers

PMID33728493
PMCPMC7966690

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.