Evidence map›Paper›PMID 33728357›Full record

ArticleOpen forum infectious diseases2021

Temporal Trends of Infective Endocarditis in Olmsted County, Minnesota, Between 1970 and 2018: A Population-Based Analysis.

Daniel C DeSimone, Brian D Lahr, Nandan S Anavekar, Muhammad R Sohail, Imad M Tleyjeh, Walter R Wilson, Larry M Baddour

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Infective endocarditis in a university hospital without on-site cardiac surgery: temporal trends over 37 years.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Daniel C DeSimoneDivision of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Brian D LahrBiomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
Nandan S AnavekarDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Muhammad R SohailDivision of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Imad M TleyjehDivision of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Walter R WilsonDivision of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Larry M BaddourDivision of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Mayo Clinic · USMayo Clinic in Florida · USKing Fahd Medical City · SA

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
NCATS NIH HHS UL1 TR000135NIA NIH HHS R01 AG034676NIA NIH HHS R33 AG058738
6 · The paper itself

Abstract

backgroundA population-based study of infective endocarditis (IE) in Olmsted County, Minnesota, provides a unique opportunity to define temporal and seasonal variations in IE incidence over an extended time period.

methodsThis was a population-based review of all adults (≥18 years) residing in Olmsted County, Minnesota, with definite or possible IE using the Rochester Epidemiology Project from January 1, 1970, through December 31, 2018. Poisson regression was used to characterize the trends in IE incidence; models were fitted with age, sex, calendar time, and season, allowing for nonlinearity and nonadditivity of their effects.

resultsOverall, 269 cases of IE were identified over a 49-year study period. The median age of IE cases was 67.2 years, and 33.8% were female. The overall age- and sex-adjusted incidence of IE was 7.9 cases per 100 000 person-years (95% CI, 7.0-8.9), with corresponding rates of 2.4, 2.4, 0.9, and 0.7 per 100 000 person-years for

conclusionsOverall, IE incidence, and specifically enterococcal IE, increased over time, while

Indexed as

dental prophylaxisenterococciguidelinesincidenceinfective endocarditisStaphylococcus aureustrendsviridans group streptococci

Identifiers

PMID33728357
PMCPMC7944350
OpenAlexW3122236932

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.