Evidence map›Paper›PMID 33728023›Full record

ReviewOxidative medicine and cellular longevity2021

Research Progress on the Mechanism of Lumbarmultifidus Injury and Degeneration.

Xianzheng Wang, Rui Jia, Jiaqi Li, Yibo Zhu, Huanan Liu, Weijian Wang, Yapeng Sun, Fei Zhang, Lei Guo, Wei Zhang

Abstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Correlation between paraspinal muscle fat infiltration and thoracic vertebral degeneration based on phantom-less QCT: a novel insight into thoracic vertebral degeneration.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xianzheng WangDepartment of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050000 Hebei Province, China.ORCID https://orcid.org/0000-0003-3435-3747
Rui JiaDepartment of Reproductive Medicine, The Second Hospital of Hebei Medical University, China.ORCID https://orcid.org/0000-0002-2837-8932
Jiaqi LiDepartment of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050000 Hebei Province, China.
Yibo ZhuSchool of Chemical Engineering, The University of Queensland, Australia.
Huanan LiuDepartment of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050000 Hebei Province, China.ORCID https://orcid.org/0000-0002-2936-3134
Weijian WangDepartment of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050000 Hebei Province, China.ORCID https://orcid.org/0000-0002-6233-9259
Yapeng SunDepartment of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050000 Hebei Province, China.
Fei ZhangDepartment of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050000 Hebei Province, China.
Lei GuoDepartment of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050000 Hebei Province, China.
Wei ZhangDepartment of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050000 Hebei Province, China.ORCID https://orcid.org/0000-0001-5972-4087

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review summarizes recent research progress in the clinical features, image manifestations, and pathological mechanism of multifidus injury. After a brief introduction to the fiber classification, innervation, blood supply, and multifidus function, some factors of multifidus injury, consisting of denervation, intraoperative incision selection and traction, and lumbar degenerative disease are overviewed. In addition, the clinical index of multifidus injury including myoglobin, creatine kinase, IL-6, C-reactive protein, the cross-sectional area of multifidus, the degree of fat infiltration, and intraoperative biopsy are summarized. Furthermore, we recommend that patients with chronic low back pain should take the long-term exercise of lumbodorsal muscles. Finally, some remaining issues, including external fixation and the imaging quantitative evaluation criteria of multifidus, need to be further explored in the future.

Indexed as

Biomedical ResearchAnimalsHumansInflammationIntervertebral Disc DegenerationLumbar VertebraeOxidative StressParaspinal Muscles

Identifiers

PMID33728023
PMCPMC7936897

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.