Evidence map›Paper›PMID 33727909›Full record

ArticleRevista panamericana de salud publica = Pan American journal of public health2021

[Toxicology of suicide cases in the state of Rio Grande do Sul, Brazil, 2017 to 2019Perfil toxicológico de los casos de suicidio en Rio Grande do Sul (Brasil), 2017-2019].

Maria Cristina Franck, Maristela Goldnadel Monteiro, Renata Pereira Limberger

Abstract readEnglish Abstract
In one paragraph

Article in Revista panamericana de salud publica = Pan American journal of public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Maria Cristina FranckInstituto-Geral de Perícias do Rio Grande do Sul (IGP-RS), Departamento de Perícias Laboratoriais Porto Alegre (RS) Brasil Instituto-Geral de Perícias do Rio Grande do Sul (IGP-RS), Departamento de Perícias Laboratoriais, Porto Alegre (RS), Brasil.
Maristela Goldnadel MonteiroPan American Health Organization (PAHO), Noncommunicable Diseases and Mental Health Washington, D.C. Estados Unidos Pan American Health Organization (PAHO), Noncommunicable Diseases and Mental Health, Washington, D.C., Estados Unidos.
Renata Pereira LimbergerUniversidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós-Graduação em Ciências Farmacêuticas Porto Alegre (RS) Brasil Universidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós-Graduação em Ciências Farmacêuticas, Porto Alegre (RS), Brasil.

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectiveTo describe the toxicology of suicide cases recorded in the state of Rio Grande do Sul, Brazil, from 2017 to 2019.

methodThe present descriptive, cross-sectional study examined all the medico-legal reports and police records related to suicide deaths in the state. Multiple correspondence analyses were performed along with independent logistic regression models having ethanol, anxiolytic and antidepressant drugs, illicit drugs, and non-medical substances as dependent variables.

resultsEthanol was investigated in 2 978 samples, with positive results in 28.5%. The odds of a positive ethanol finding were 0.5 time higher (95%CI: 1.1; 2.2) for suicides occurring at night, 1.0 (95%CI: 1.4; 2.9) time higher for suicides occurring on weekends, and 0.9 (95%CI: 1.3; 2.7) time higher in individuals with a prior criminal record. Investigation of psychotropic drugs (2 900 samples) was positive in 30.4% samples. Anxiolytics were the most common medication detected, with 1.5 (95%CI: 1.6; 4.1) time higher odds of occurrence in women and 0.8 time higher odds (95%CI: 1.2; 2.7) for suicides occurring in the fall-winter. The odds of detecting illicit drugs (n = 338) were 4.1 times higher (95%CI: 1.9; 14.4) in the regions of Pelotas (south of the state) vs. Passo Fundo (north), and 1.2 (95%CI: 1.3; 3.6) time higher in cases with positive ethanol results, without significant difference between adolescents and adults.

conclusionsDespite the lack of evidence on causality, the present results support a link between suicide and several psychoactive drugs. Medico-legal experts should be guided regarding the need to perform toxicological tests in all suicide cases.

Indexed as

Brazilethanolforensic toxicologymultivariate analysispsychotropic drugSuicide

Identifiers

PMID33727909
PMCPMC7954196

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