Evidence map›Paper›PMID 33727830›Full record

ReviewOncoTargets and therapy2021

Current and Emerging Therapeutic Options for Hairy Cell Leukemia Variant.

Qiuying Liu, Nicholas Harris, Narendranath Epperla, Leslie A Andritsos

Abstract readReview
In one paragraph

Review in OncoTargets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Advances in the Treatment of Hairy Cell Leukemia Variant.Current treatment options in oncology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qiuying LiuDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.
Nicholas HarrisDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.
Narendranath EpperlaDivision of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.ORCID 0000-0002-8216-3457
Leslie A AndritsosDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.ORCID 0000-0003-0222-1766

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hairy cell leukemia variant (HCL-v) is a rare B-cell lymphoproliferative disorder with distinct immunophenotypic and molecular characteristics when compared to classical hairy cell leukemia (HCL-c). In contrast to the enormous progress in therapeutic options for HCL-c, HCL-v remains a therapeutic challenge due to inferior outcomes with standard chemoimmunotherapy and BCR signaling pathway inhibitors, and due to the fact that HCL-v has limited molecular therapeutic targets. In addition, because of the rarity of the disease, there is a paucity of later phase studies or multicenter trials to guide treatment decisions. In this article, we briefly review the diagnostic criteria and clinical characteristics of HCL-v and present a comprehensive overview of current therapeutic options in HCL-v.

Indexed as

HCL-cHCL-vrare lymphoid malignanciessalvage therapy

Identifiers

PMID33727830
PMCPMC7955867

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.