Evidence map›Paper›PMID 33727754›Full record

ReviewRevista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia2021

Coronavirus Disease 2019 and Herbal Therapy: Pertinent Issues Relating to Toxicity and Standardization of Phytopharmaceuticals.

Kayode Komolafe, Titilope Ruth Komolafe, Toluwase Hezekiah Fatoki, Afolabi Clement Akinmoladun, Bartholomew I C Brai, Mary Tolulope Olaleye, Afolabi Akintunde Akindahunsi

Open access · bronzeAbstract readReview
In one paragraph

Review in Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Toxicological Evaluation andEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  7. Article
  8. The Role of Micronutrients to Support Immunity for COVID-19 Prevention.Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia · 2021
    Review
  9. Structural Diversity and Biological Potential of Alkaloids from the GenusRevista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia · 2021
    Review
  10. Flavonoids fromRevista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia · 2021
    Article
  11. Effects of Anacardic Acid Monoene on the Respiratory System of Mice Submitted to Acute Respiratory Distress Syndrome.Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia · 2021
    Article
  12. Antiviral Properties of Baicalin: a Concise Review.Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kayode KomolafeDepartment of Biochemistry, Faculty of Science, Federal University Oye-Ekiti, PMB 373, Oye-Ekiti, Nigeria.ORCID 0000-0003-3319-5863
Titilope Ruth KomolafeDepartment of Biochemistry, Faculty of Science, Federal University Oye-Ekiti, PMB 373, Oye-Ekiti, Nigeria.ORCID https://orcid.org/0000-0002-2561-1903
Toluwase Hezekiah FatokiDepartment of Biochemistry, School of Sciences, The Federal University of Technology, PMB 704, Akure, Nigeria.ORCID https://orcid.org/0000-0003-3202-9855
Afolabi Clement AkinmoladunDepartment of Biochemistry, School of Sciences, The Federal University of Technology, PMB 704, Akure, Nigeria.ORCID https://orcid.org/0000-0003-0901-1235
Bartholomew I C BraiDepartment of Biochemistry, Faculty of Science, Federal University Oye-Ekiti, PMB 373, Oye-Ekiti, Nigeria.ORCID https://orcid.org/0000-0001-7410-568X
Mary Tolulope OlaleyeDepartment of Biochemistry, School of Sciences, The Federal University of Technology, PMB 704, Akure, Nigeria.ORCID https://orcid.org/0000-0003-3239-4289
Afolabi Akintunde AkindahunsiDepartment of Biochemistry, School of Sciences, The Federal University of Technology, PMB 704, Akure, Nigeria.ORCID https://orcid.org/0000-0003-1969-1967
Federal University of Technology · NGFederal University Oye Ekiti · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is a virulent viral disease that has now become a public health emergency of global significance and still without an approved treatment regimen or cure. In the absence of curative drugs and with vaccines development still in progress, alternative approaches to stem the tide of the pandemic are being considered. The potential of a phytotherapeutic approach in the management of the dreaded disease has gained attention, especially in developing countries, with several claims of the development of anti-COVID-19 herbal formulations. This is a plausible approach especially with the increasing acceptance of herbal medicine in both alternative and orthodox medical practices worldwide. Also, the established efficacy of herbal remedies in the treatment of numerous viral diseases including those caused by coronaviruses, as well as diseases with symptoms associated with COVID-19, presents a valid case for serious consideration of herbal medicine in the treatment of COVID-19. However, there are legitimate concerns and daunting challenges with the use of herbs and herbal products. These include issues of quality control, unethical production practice, inadequate information on the composition, use and mechanisms, weak regulatory policies, herb-drug interactions and adverse reactions, and the tendency for abuse. This review discusses the feasibility of intervention with herbal medicine in the COVID-19 pandemic and the need to take proactive measures to protect public health by improving the quality and safety of herbal medicine deployed to combat the disease. Graphical abstract. Supplementary Information: The online version contains supplementary material available at 10.1007/s43450-021-00132-x.

Indexed as

Drug controlHerbal medicineHerb-drug interactionPhytochemicalsStandardizationTraditional medicine

Identifiers

PMID33727754
PMCPMC7951132
OpenAlexW3134090298

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.