Evidence map›Paper›PMID 33727749›Full record

ArticleNagoya journal of medical science2021

Genome-wide association study of serum prostate-specific antigen levels based on 1000 Genomes imputed data in Japanese: the Japan Multi-Institutional Collaborative Cohort Study.

Asahi Hishida, Masahiro Nakatochi, Takashi Tamura, Mako Nagayoshi, Rieko Okada, Yoko Kubo, Mineko Tsukamoto, Yuka Kadomatsu, Sadao Suzuki, Takeshi Nishiyama and 22 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nagoya journal of medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 13 institutions in 1 country.

Asahi HishidaDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Masahiro NakatochiPublic Health Informatics Unit, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Takashi TamuraDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Mako NagayoshiDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Rieko OkadaDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yoko KuboDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Mineko TsukamotoDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yuka KadomatsuDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Sadao SuzukiDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Takeshi NishiyamaDepartment of Public Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Nagato KuriyamaDepartment of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Isao WatanabeDepartment of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Toshiro TakezakiDepartment of International Island and Community Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Daisaku NishimotoSchool of Health Sciences, Faculty of Medicine, Kagoshima University, Kagoshima, Japan.
Kiyonori KurikiLaboratory of Public Health, Division of Nutritional Sciences, School of Food and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan.
Kokichi ArisawaDepartment of Preventive Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Sakurako Katsuura-KamanoDepartment of Preventive Medicine, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Haruo MikamiCancer Prevention Center, Chiba Cancer Center Research Institute, Chiba, Japan.
Miho KusakabeCancer Prevention Center, Chiba Cancer Center Research Institute, Chiba, Japan.
Isao OzeDivision of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan.
Yuriko N KoyanagiDivision of Cancer Information and Control, Aichi Cancer Center Research Institute, Nagoya, Japan.
Yasuyuki NakamuraDepartment of Public Health, Shiga University of Medical Science, Otsu, Japan.
Aya KadotaDepartment of Public Health, Shiga University of Medical Science, Otsu, Japan.
Chisato ShimanoeClinical Research Center, Saga University Hospital, Saga, Japan.
Keitaro TanakaDepartment of Preventive Medicine, Faculty of Medicine, Saga University, Saga, Japan.
Hiroaki IkezakiDepartment of Comprehensive General Internal Medicine, Kyushu University Graduate School of Medical Sciences, Faculty of Medical Sciences, Fukuoka, Japan.
Masayuki MurataDepartment of General Internal Medicine, Kyushu University Hospital, Fukuoka, Japan.
Michiaki KuboLaboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Yukihide MomozawaLaboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Kenji TakeuchiDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kenji WakaiDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
for the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Group
Nagoya University · JPAichi Cancer Center · JPChiba Cancer Center · JPKagoshima University · JPKyoto Prefectural University of Medicine · JPNagoya City University · JPRIKEN Center for Integrative Medical Sciences · JPSaga University · JPShiga University of Medical Science · JPTokushima University · JPKyushu University · JPKyushu University Hospital · JPUniversity of Shizuoka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is emerging as a significant global public health burden. The incidence and prevalence of prostate cancer has increased in Japan, as westernized lifestyles become more popular. Recent advances in genetic epidemiology, including genome-wide association studies (GWASs), have identified considerable numbers of human genetic factors associated with diseases. Several GWASs have reported significant loci associated with serum prostate-specific antigen (PSA) levels. One GWAS, which was based on classic GWAS microarray measurements, has been reported for Japanese so far. In the present study, we conducted a GWAS of serum PSA using 1000Genomes imputed GWAS data (n =1,216) from the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study, to detect candidate novel genetic loci that influence serum PSA levels in Japanese. The association of SNPs/genetic variants with serum PSA as a continuous variable was tested using the linear Wald test. SNP rs10000006 in

Indexed as

AdultCohort StudiesGenetic Predisposition to DiseaseGenome-Wide Association StudyGenotypeHumansJapanKallikreinsMaleMiddle AgedPolymorphism, Single NucleotideProstate-Specific AntigenProstatic NeoplasmsReproducibility of ResultsTransferases (Other Substituted Phosphate Groups)KallikreinsKLK3 protein, humanProstate-Specific AntigenSGMS2 protein, humanTransferases (Other Substituted Phosphate Groups)genetic polymorphismsGWASJ-MICC StudyPSA

Identifiers

PMID33727749
PMCPMC7938099
OpenAlexW3138551282

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.