ArticleScientific reports2021
Detection of horizontal gene transfer in the genome of the choanoflagellate Salpingoeca rosetta.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 23 citations in OpenAlex.
- Characterizing the evolution and potential function of eleven horizontally transferred genes in amphioxus.Communications biology · 2026Article
- Detection and functional analysis of horizontal gene transfer events in the ciliateFrontiers in microbiology · 2026Article
- Leveraging FracMinHash Containment for GenomicbioRxiv : the preprint server for biology · 2025Article
- Metagenomic Insight into the Associated Microbiome in Plasmodia of Myxomycetes.Microorganisms · 2024Article
- A broad survey of choanoflagellates revises the evolutionary history of the Shaker family of voltage-gated KProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genomic insights into the evolution and adaptation of secondary metabolite gene clusters in fungicolous species Cladobotryum mycophilum ATHUM6906.G3 (Bethesda, Md.) · 2024Article
- Invasive mussels fashion silk-like byssus via mechanical processing of massive horizontally acquired coiled coils.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Cross-phyla protein annotation by structural prediction and alignment.Genome biology · 2023Article
- Three-dimensional flagella structures from animals' closest unicellular relatives, the Choanoflagellates.eLife · 2022Article
- Old genes in new places: A taxon-rich analysis of interdomain lateral gene transfer events.PLoS genetics · 2022Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Horizontal gene transfer (HGT), the movement of heritable materials between distantly related organisms, is crucial in eukaryotic evolution. However, the scale of HGT in choanoflagellates, the closest unicellular relatives of metazoans, and its possible roles in the evolution of animal multicellularity remains unexplored. We identified at least 175 candidate HGTs in the genome of the colonial choanoflagellate Salpingoeca rosetta using sequence-based tests. The majority of these were orthologous to genes in bacterial and microalgal lineages, yet displayed genomic features consistent with the rest of the S. rosetta genome-evidence of ancient acquisition events. Putative functions include enzymes involved in amino acid and carbohydrate metabolism, cell signaling, and the synthesis of extracellular matrix components. Functions of candidate HGTs may have contributed to the ability of choanoflagellates to assimilate novel metabolites, thereby supporting adaptation, survival in diverse ecological niches, and response to external cues that are possibly critical in the evolution of multicellularity in choanoflagellates.
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