Evidence map›Paper›PMID 33727473›Full record

ArticleIndian journal of ophthalmology2021

Acute graft rejection in a COVID-19 patient: Co-incidence or causal association?

Garima Singh, Umang Mathur

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Indian journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Garima SinghDepartment of Cornea, Cataract and Refractive Services. Dr Shroff's Charity Eye Hospital, New Delhi, India.
Umang MathurDepartment of Cornea, Cataract and Refractive Services. Dr Shroff's Charity Eye Hospital, New Delhi, India.
Dr. Shroff’s Charity Eye Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 32-year-old man with a clear and compact graft following a penetrating keratoplasty 6 years back, developed an episode of acute graft rejection, coinciding with the COVID-19 disease. Subsequent to the infection with the novel coronavirus, he developed symptoms of acute graft rejection concurrent with the development of respiratory distress and peak systemic symptoms. This was the phase of cytokine storm as evidenced by the raised inflammatory markers in his blood tests. Such a case of acute corneal graft rejection coinciding with SARS-CoV-2 infection has been reported only once in the literature and this unique association needs to be researched further.

Indexed as

Keratoplasty, PenetratingSARS-CoV-2Acute DiseaseAdultCataract ExtractionCorneal DiseasesCOVID-19COVID-19 Drug TreatmentCOVID-19 Nucleic Acid TestingCytokinesEye Infections, ViralGlucocorticoidsGraft RejectionHumansIncidenceInflammation MediatorsCytokinesGlucocorticoidsInflammation MediatorsPrednisoloneAcute corneal graft rejectionCOVID-19cytokine stormSARS-CoV-2

Identifiers

PMID33727473
PMCPMC8012967
OpenAlexW3138321217

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.