Evidence map›Paper›PMID 33727356›Full record

ArticlemBio2021

The ChiS-Family DNA-Binding Domain Contains a Cryptic Helix-Turn-Helix Variant.

Catherine A Klancher, George Minasov, Ram Podicheti, Douglas B Rusch, Triana N Dalia, Karla J F Satchell, Matthew B Neiditch, Ankur B Dalia

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Catherine A KlancherDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
George MinasovCenter for Structural Genomics of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Ram PodichetiCenter for Genomics and Bioinformatics, Indiana University, Bloomington, Indiana, USA.
Douglas B RuschCenter for Genomics and Bioinformatics, Indiana University, Bloomington, Indiana, USA.
Triana N DaliaDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
Karla J F SatchellCenter for Structural Genomics of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0003-3274-7611
Matthew B NeiditchDepartment of Microbiology, Biochemistry, and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical Health Sciences, Newark, New Jersey, USA.
Ankur B DaliaDepartment of Biology, Indiana University, Bloomington, Indiana, USA ankdalia@indiana.edu.ORCID 0000-0003-2203-1230
Indiana University Bloomington · USNorthwestern University · USRutgers, The State University of New Jersey · US

Funding

Mechanisms and regulation of horizontal gene transfer by natural transformation in Vibrio choleraeR35GM128674 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Ankur Dalia · 2018 to 2026
$3.8M
NIAID NIH HHS HHSN272201700060CNIGMS NIH HHS R35 GM128674
6 · The paper itself

Abstract

Sequence-specific DNA-binding domains (DBDs) are conserved in all domains of life. These proteins carry out a variety of cellular functions, and there are a number of distinct structural domains already described that allow for sequence-specific DNA binding, including the ubiquitous helix-turn-helix (HTH) domain. In the facultative pathogen

Indexed as

Protein DomainsBacterial ProteinsDNA-Binding ProteinsHelix-Turn-Helix MotifsMutagenesisProtein BindingVibrio choleraeBacterial ProteinsDNA-Binding ProteinsDNA-binding proteinsmolecular geneticsstructural biology

Identifiers

PMID33727356
PMCPMC8092284
OpenAlexW3138143728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.