Evidence map›Paper›PMID 33727345›Full record

ArticlemBio2021

A Conserved Class II Type Thioester Domain-Containing Adhesin Is Required for Efficient Conjugation in Bacillus subtilis.

César Gago-Córdoba, Jorge Val-Calvo, David Abia, Alberto Díaz-Talavera, Andrés Miguel-Arribas, Rocío Aguilar Suárez, Jan Maarten van Dijl, Ling Juan Wu, Wilfried J J Meijer

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Assessment ofMicroorganisms · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

César Gago-CórdobaCentro de Biología Molecular Severo Ochoa (CSIC-UAM), Universidad Autónoma, Madrid, Spain.ORCID 0000-0001-7470-4033
Jorge Val-CalvoCentro de Biología Molecular Severo Ochoa (CSIC-UAM), Universidad Autónoma, Madrid, Spain.ORCID 0000-0001-6441-8113
David AbiaCentro de Biología Molecular Severo Ochoa (CSIC-UAM), Universidad Autónoma, Madrid, Spain.
Alberto Díaz-TalaveraCentro de Biología Molecular Severo Ochoa (CSIC-UAM), Universidad Autónoma, Madrid, Spain.
Andrés Miguel-ArribasCentro de Biología Molecular Severo Ochoa (CSIC-UAM), Universidad Autónoma, Madrid, Spain.
Rocío Aguilar SuárezUniversity of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0003-4452-065X
Jan Maarten van DijlUniversity of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0002-5688-8438
Ling Juan WuCentre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0003-2432-8820
Wilfried J J MeijerCentro de Biología Molecular Severo Ochoa (CSIC-UAM), Universidad Autónoma, Madrid, Spain wmeijer@cbm.csic.es.ORCID 0000-0003-1842-0049
Centro de Biología Molecular Severo Ochoa · ESUniversity Medical Center Groningen · NLNewcastle University · GB

Funding

Wellcome Trust 209500/Z/17/Z
6 · The paper itself

Abstract

Conjugation, the process by which a DNA element is transferred from a donor to a recipient cell, is the main horizontal gene transfer route responsible for the spread of antibiotic resistance and virulence genes. Contact between a donor and a recipient cell is a prerequisite for conjugation, because conjugative DNA is transferred into the recipient via a channel connecting the two cells. Conjugative elements encode proteins dedicated to facilitating the recognition and attachment to recipient cells, also known as mating pair formation. A subgroup of the conjugative elements is able to mediate efficient conjugation during planktonic growth, and mechanisms facilitating mating pair formation will be particularly important in these cases. Conjugative elements of Gram-negative bacteria encode conjugative pili, also known as sex pili, some of which are retractile. Far less is known about mechanisms that promote mating pair formation in Gram-positive bacteria. The conjugative plasmid pLS20 of the Gram-positive bacterium

Indexed as

Adhesins, BacterialBacillus subtilisBacterial ProteinsConjugation, GeneticDNA, BacterialGene Transfer, HorizontalOperonPlasmidsAdhesins, BacterialBacterial ProteinsDNA, Bacterialadhesion moleculesantibiotic resistanceconjugationGram-positive bacteriamatingplasmidsthioester domain

Identifiers

PMID33727345
PMCPMC8092201
OpenAlexW3136931376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.