ArticleClinical epigenetics2021

BET bromodomain inhibitors PFI-1 and JQ1 are identified in an epigenetic compound screen to enhance C9ORF72 gene expression and shown to ameliorate C9ORF72-associated pathological and behavioral abnormalities in a C9ALS/FTD model.

Esteban Quezada et al.PubMed ↗Full text ↗Publisher ↗

No numbers read from the abstract.