ArticleEvoDevo2021
Post-metamorphic skeletal growth in the sea urchin Paracentrotus lividus and implications for body plan evolution.
Article in EvoDevo, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- Single-nucleus profiling highlights the all-brain echinoderm nervous system.Science advances · 2025Article
- Antero-posterior patterning in the brittle star Amphipholis squamata and the evolution of echinoderm body plans.EvoDevo · 2025Article
- Structural and molecular distinctions of primary and secondary spines in the sea urchin Lytechinus variegatus.Scientific reports · 2024Article
- A feather star is born: embryonic development and nervous system organization in the crinoidOpen biology · 2024Article
- See-Star: a versatile hydrogel-based protocol for clearing large, opaque and calcified marine invertebrates.EvoDevo · 2024Article
- Composite material in the sea urchinJournal of the Royal Society, Interface · 2024Article
- The Metameric Echinoderm.Integrative organismal biology (Oxford, England) · 2024Article
- Characterization of thyrotropin-releasing hormone producing neurons in sea urchin, from larva to juvenile.Frontiers in neuroscience · 2024Article
- Article
- Cambrian edrioasteroid reveals new mechanism for secondary reduction of the skeleton in echinoderms.Proceedings. Biological sciences · 2022Article
- The Evolution of Biomineralization through the Co-Option of Organic Scaffold Forming Networks.Cells · 2022Review
- Developmental atlas of the indirect-developing sea urchinFrontiers in cell and developmental biology · 2022Article
- The Development and Neuronal Complexity of Bipinnaria Larvae of the Sea Star Asterias rubens.Integrative and comparative biology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUnderstanding the molecular and cellular processes that underpin animal development are crucial for understanding the diversity of body plans found on the planet today. Because of their abundance in the fossil record, and tractability as a model system in the lab, skeletons provide an ideal experimental model to understand the origins of animal diversity. We herein use molecular and cellular markers to understand the growth and development of the juvenile sea urchin (echinoid) skeleton.
resultsWe developed a detailed staging scheme based off of the first ~ 4 weeks of post-metamorphic life of the regular echinoid Paracentrotus lividus. We paired this scheme with immunohistochemical staining for neuronal, muscular, and skeletal tissues, and fluorescent assays of skeletal growth and cell proliferation to understand the molecular and cellular mechanisms underlying skeletal growth and development of the sea urchin body plan.
conclusionsOur experiments highlight the role of skeletogenic proteins in accretionary skeletal growth and cell proliferation in the addition of new metameric tissues. Furthermore, this work provides a framework for understanding the developmental evolution of sea urchin body plans on macroevolutionary timescales.
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