ArticleBMC public health2021
The association between daily total physical activity and risk of cardiovascular disease among hypertensive patients: a 10-year prospective cohort study in China.
Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 12 citations in OpenAlex.
- Silent Thyroid, Loud Lipids: The Hidden Link in Asymptomatic Adults.Juntendo medical journal · 2026Article
- [Different Types of Obesity Play a Modifying Role in the Association Between Physical Activity and Metabolic Dysfunction-Associated Fatty Liver Disease].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Article
- Joint association of sleep quality and physical activity with hypertension: a cross-sectional population study in agricultural workers.Frontiers in cardiovascular medicine · 2025Article
- The Jiangsu Biobank for the Prevention and Control of Diabetes (JBPCD) in China.European journal of epidemiology · 2024Article
- Association between physical activity and clinical outcomes in high-risk hypertension: Post-hoc analysis of SPRINT.American journal of preventive cardiology · 2023Article
- Dog ownership may promote cardiometabolic health in U.S. military veterans.Scientific reports · 2023Article
- Association of healthy lifestyle with incident cardiovascular diseases among hypertensive and normotensive Chinese adults.Frontiers in cardiovascular medicine · 2023Article
- Interactions between physical activity and psychological factors in the association with the risk of lean type 2 diabetes mellitus.Diabetes & vascular disease researchArticle
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12 authors at 5 institutions in 2 countries.
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Abstract
backgroundThe effect of high levels of physical activity and relationship between daily total physical activity and the risk of cardiovascular disease (CVD) among hypertensive people were not clear. This study aimed to explore the optimum level of physical activity for CVD prevention.
methodsData used in the present study was derived from the sub-study of China Kadoorie Biobank study (CKB) in Jiangsu province of China. The CKB was a prospective cohort study established during 2004-2008. At baseline, 53,259 participants aged 35-74 years were recruited for the CKB Jiangsu sub-study conducted in Wuzhong district of Suzhou City. Among those 53,259 participants, the 20,179 hypertensive individuals were our study population. The outcome events were cardiovascular diseases (CVDs), while the independent variable was total daily physical activity. The Cox proportional hazard models were introduced to investigate the association between total physical activity and CVDs, reporting as hazard ratios (HR) and 95% confidence intervals (CIs).
resultsDuring a 10.1-year follow-up, 2419 CVD cases were identified. After adjustment for potential confounding factors, compared with participants at the lowest level of daily total physical activity, the hazard ratios for CVDs were 0.87 (95%CI: 0.79-0.97), 0.73 (95%CI: 0.65-0.83) and 0.75 (95%CI: 0.65-0.85) for participants within 2, 3 and 4 quartiles of physical activity. Such a negative association between total physical activity and CVDs were also observed among participants by gender and age-group, but within patients with stage 1 hypertension only. Moreover, the association of physical activity with CVDs was U-shape and the lowest HR (0.63, 95%CI: 0.54-0.74) was observed at 35.4 MET-h/d of total physical activity.
conclusionsTotal daily physical activity was negatively associated with CVDs among hypertensive adults in China, and this association was U-shape. It has some public health implications that community-based total physical activity intervention campaigns can be of help for CVDs prevention among hypertensive people in China.
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