Evidence map›Paper›PMID 33726612›Full record

ArticleSubstance use & misuse2021

Associations between Adverse Childhood Experiences and Performance-Enhancing Substance Use among Young Adults.

Kyle T Ganson, Stuart B Murray, Deborah Mitchison, Misty A W Hawkins, Harley Layman, Jennifer Tabler, Jason M Nagata

Open access · greenAbstract read
In one paragraph

Article in Substance use & misuse, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Kyle T GansonFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Canada.ORCID 0000-0003-3889-3716
Stuart B MurrayDepartment of Psychiatry and the Behavioral Sciences, University of Southern California, Los Angeles, California, USA.ORCID 0000-0002-5588-2915
Deborah MitchisonTranslational Health Research Institute, School of Medicine, Western Sydney University, Sydney, Australia.
Misty A W HawkinsDepartment of Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.ORCID 0000-0002-3825-639X
Harley LaymanDepartment of Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.
Jennifer TablerDepartment of Criminal Justice and Sociology, College of Arts and Sciences, University of Wyoming, Laramie, Wyoming, USA.ORCID 0000-0003-2256-327X
Jason M NagataDivision of Adolescent and Young Adult Medicine, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-6541-0604
Oklahoma State University · USTranslational Research Institute · AUUniversity of California, San Francisco · USUniversity of Southern California · USUniversity of Toronto · CAUniversity of Wyoming · US

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
NICHD NIH HHS P01 HD031921
6 · The paper itself

Abstract

BACKGROUND AND

objectiveAdverse childhood experiences (ACEs) are associated with negative health outcomes, yet their associations with performance-enhancing substance (PES) use are unclear. This study aimed to determine whether ACEs predict greater use of legal and illegal PES in young adults.

methodsWe analyzed data from the National Longitudinal Study of Adolescent to Adult Health (

resultsSexual abuse had the greatest effect and predicted higher odds of legal PES use (men: adjusted odds ratio [AOR] 1.66, 95% confidence interval [CI] 1.06-2.59; women: AOR 3.74, 95% CI 1.63-8.59) and AAS use (men: AOR 8.89, 95% CI 5.37-14.72; women: AOR 5.73, 95% CI 2.31-14.18). Among men, a history of physical abuse (AOR 3.04, 95% CI 2.05-4.52), being left alone by a parent/guardian (AOR 2.33, 95% CI 1.50-3.60), and basic needs not being met (AOR 3.47, 95% CI 2.30-5.23) predicted higher odds of AAS use. Among women, basic needs not being met (AOR 2.94, 95% CI 1.43-6.04) predicted higher odds of AAS use. Among both men and women, greater number of cumulative ACEs predicted higher odds of both legal and illegal PES use.

conclusionsACEs predict greater PES use among young adults. Clinicians should monitor for PES use among those who have experienced ACEs and provide psychoeducation on the adverse effects associated with PES use.

Indexed as

Adverse Childhood ExperiencesChild AbusePerformance-Enhancing SubstancesSex OffensesAdolescentChildFemaleHumansLongitudinal StudiesMaleOdds RatioYoung AdultPerformance-Enhancing SubstancesAdverse childhood experiencesanabolic steroidscreatine monohydratesexual abuseyoung adults

Identifiers

PMID33726612
PMCPMC11385237
OpenAlexW3138545152

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.