ArticlePhysics in medicine and biology2021
Super-resolution ultrasound localization microscopy based on a high frame-rate clinical ultrasound scanner: an in-human feasibility study.
Registry-linked trialOpen access · greenAbstract read
In one paragraph
Article in Physics in medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05754814 (SUper-Resolution Ultrasound Imaging of Erythrocytes), which is not on this map. Cited by 64 papers.
0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
12.6field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SUper-Resolution Ultrasound Imaging of Erythrocytes (SURE) in Normal and Malignant Lymph Nodes
Who cites it
64 citing papers in PubMed, 145 citations in OpenAlex.
- Fast 3-D Ultrasound Localization Microscopy via Projection-Based Processing Framework.IEEE transactions on medical imaging · 2026Article
- Super-resolution contrast-enhanced ultrasound: recent advances.Ultrasonography (Seoul, Korea) · 2026Article
- Prospective Pilot Study of Ultrasound Resolution Microscopy Imaging (URM) for Differentiating Benign and Malignant Breast Lesions: A Quantitative Microvascular Parameter Analysis.Diagnostics (Basel, Switzerland) · 2026Article
- A Case of Misdiagnosed Hepatic Sarcoidosis: Evaluating Ultrasound Resolution Microscopy for Differentiating Hepatic Sarcoidosis from Hepatocellular Carcinoma.Diagnostics (Basel, Switzerland) · 2026Article
- Advancing Ultrasound Beamforming With Deep Learning: A Comprehensive Review of Methods, Datasets, Benchmarks, and Computational Challenges.International journal of biomedical imaging · 2026Review
- Differentiation of Benign and Malignant BI-RADS 4-5 Breast Lesions Using Ultrasound Localization Microscopy-Derived Microvascular Biomarkers: A Prospective Study.Breast cancer (Dove Medical Press) · 2026Article
- A reproducible ultrasound localization microscopy framework for the quantitative imaging of hepatocellular carcinoma on a clinical ultrasound system.Theranostics · 2026Article
- The value of multimodal ultrasound imaging in differentiating HER2-positive breast cancer.Frontiers in oncology · 2026Article
- Emerging Technologies for Exploring the Cellular Mechanisms in Vascular Diseases.International journal of molecular sciences · 2025Review
- Laser Ultrasound Super-Resolution Imaging for Multi-Parametric Non-Invasive Volumetric Characterization of Brain Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Label-Free Hemodynamic Mapping via Ultrafast Power Doppler-Enhanced Photoacoustic Imaging reveals early therapy-induced functional changes in the tumor.bioRxiv : the preprint server for biology · 2025Article
- Ultrasound super-resolution microvascular imaging of kidney microvascular alterations in acute kidney injury on a clinical ultrasound scanner.European journal of medical research · 2025Article
- Multi-lens ultrasound arrays enable large scale three-dimensional micro-vascularization characterization over whole organs.Nature communications · 2025Article
- High-Resolution Contrast-Enhanced Ultrasound with SRCEUS for Assessing the Intrahepatic Microvasculature and Shunts in Patients with Hereditary Haemorrhagic Teleangiectasia (Osler's Disease).Life (Basel, Switzerland) · 2025Article
- High-Volume Acquisition Rate Nonlinear Imaging Enables Robust 3-D Ultrasound Localization Microscopy.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025Article
- Ultrasound matrix imaging for 3D transcranial in vivo localization microscopy.Science advances · 2025Article
- Human lymph node microvascular imaging using a fast contrast-free super-resolution ultrasound technique.Scientific reports · 2025Article
- Super-Resolution Contrast-Enhanced Ultrasound Examination Down to the Microvasculature Enables Quantitative Analysis of Liver Lesions: First Results.Life (Basel, Switzerland) · 2025Article
- Differentiation of benign and malignant breast lesions by ultrasound localization microscopy.Insights into imaging · 2025Article
- Progresses and clinical application of super-resolution ultrasound imaging: a narrative review.The ultrasound journal · 2025Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 2 countries.
Chengwu HuangDepartment of Radiology, Mayo Clinic College of Medicine and Science, Mayo Clinic, Rochester, MN, United States of America.ORCID 0000-0003-0745-821X
Wei ZhangDepartment of Ultrasound, Guangdong Key Laboratory of Liver Disease Research, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.ORCID 0000-0001-7940-9359
Ping GongDepartment of Radiology, Mayo Clinic College of Medicine and Science, Mayo Clinic, Rochester, MN, United States of America.ORCID 0000-0002-9652-1657
U-Wai LokDepartment of Radiology, Mayo Clinic College of Medicine and Science, Mayo Clinic, Rochester, MN, United States of America.
Shanshan TangDepartment of Radiology, Mayo Clinic College of Medicine and Science, Mayo Clinic, Rochester, MN, United States of America.
Tinghui YinDepartment of Ultrasound, Guangdong Key Laboratory of Liver Disease Research, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Xirui ZhangShenzhen Mindray Bio-Medical Electronics Co. Ltd, Shenzhen, Guangdong, People's Republic of China.ORCID 0000-0002-4305-4813
Lei ZhuShenzhen Mindray Bio-Medical Electronics Co. Ltd, Shenzhen, Guangdong, People's Republic of China.
Maodong SangShenzhen Mindray Bio-Medical Electronics Co. Ltd, Shenzhen, Guangdong, People's Republic of China.
Pengfei SongBeckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, United States of America.
Rongqin ZhengDepartment of Ultrasound, Guangdong Key Laboratory of Liver Disease Research, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.
Shigao ChenDepartment of Radiology, Mayo Clinic College of Medicine and Science, Mayo Clinic, Rochester, MN, United States of America.
Mayo Clinic in Arizona · USMindray (China) · CNSun Yat-sen University · CNUniversity of Illinois Urbana-Champaign · US
Funding
High-resolution High-speed Photoacoustic and Ultrasound Imaging of SmallVessel Functions in Ischemic StrokeR01NS111039 · NINDS · DUKE UNIVERSITY · PI YAO, JUNJIE · 2019 to 2023
$2.7MQuantitative Ultrasound Imaging Biomarkers of Crohn's DiseaseR01DK120559 · NIDDK · MAYO CLINIC ROCHESTER · PI BRUINING, DAVID HENRY, CHEN, SHIGAO · 2019 to 2022
$1.7MEarly prediction of colorectal liver metastases treatment response with ultrasound microvessel imagingR00CA214523 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SONG, PENGFEI · 2019 to 2021
$684kNCI NIH HHS R00 CA214523NIDDK NIH HHS R01 DK120559NINDS NIH HHS R01 NS111039
Abstract
Non-invasive detection of microvascular alterations in deep tissues
Indexed as
MicrobubblesMicroscopyUltrasonographyFeasibility StudiesHumansMicrovesselscontrast-enhanced ultrasoundhigh frame-ratemicrobubblemicrovascular imagingsuper-resolution ultrasoundultrasound localization microscopy
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
NCT05754814ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.