Evidence map›Paper›PMID 33725283›Full record

ArticleInflammopharmacology2021

Anti-inflammatory effects of Chrysophyllum cainito fruit extract in lipopolysaccharide-stimulated mouse peritoneal macrophages.

Víctor Ermilo Arana-Argáez, Gonzalo J Mena-Rejón, Julio Cesar Torres-Romero, Julio Cesar Lara-Riegos, Gumersindo López-Mirón, Rubén M Carballo

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Inflammopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Effects of Low Molecular Weight Peptides from Red Shrimp (International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Víctor Ermilo Arana-ArgáezLaboratorio de Farmacología, Facultad de Química, Universidad Autónoma de Yucatán, Mérida, Yucatán, México.
Gonzalo J Mena-RejónLaboratorio de Química Farmacéutica, Facultad de Química, Universidad Autónoma de Yucatán, Calle 43, No 613 x calle 90, Col. Inalámbrica, CP. 97069, Mérida, Yucatán, México.
Julio Cesar Torres-RomeroLaboratorio de Bioquímica y Genética Molecular, Facultad de Química, Universidad Autónoma de Yucatán, Mérida, Yucatán, México.
Julio Cesar Lara-RiegosLaboratorio de Bioquímica y Genética Molecular, Facultad de Química, Universidad Autónoma de Yucatán, Mérida, Yucatán, México.
Gumersindo López-MirónLaboratorio de Química Farmacéutica, Facultad de Química, Universidad Autónoma de Yucatán, Calle 43, No 613 x calle 90, Col. Inalámbrica, CP. 97069, Mérida, Yucatán, México.
Rubén M CarballoLaboratorio de Química Farmacéutica, Facultad de Química, Universidad Autónoma de Yucatán, Calle 43, No 613 x calle 90, Col. Inalámbrica, CP. 97069, Mérida, Yucatán, México. ruben.marrero@correo.uady.mx.ORCID http://orcid.org/0000-0003-4093-6295
Autonomous University of Yucatán · MX

Funding

Consejo Nacional de Ciencia y Tecnología CB-2013-01/221886
6 · The paper itself

Abstract

The present paper sought to investigate the in vitro and in vivo anti-inflammatory effects of the methanolic extract (ME), hexane-ethyl acetate fraction E (FE) found in Chrysophyllum cainito fruits (CCF), as well the lupeol acetate (LA) obtained from FE on lipopolysaccharide (LPS)-stimulated mouse peritoneal macrophages. The macrophages were treated with ME, FE or LA at various concentrations and the viability of cells was determined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide method. Production of pro-inflammatory (IL-1β, IL-6, and TNF-α) and anti-inflammatory (IL-10) cytokines, as well as the nitric oxide (NO) and hydrogen peroxide (H

Indexed as

AnimalsAnti-Inflammatory AgentsCarrageenanCell SurvivalDose-Response Relationship, DrugEdemaFruitInflammationLipopolysaccharidesMacrophages, PeritonealMaleMiceMice, Inbred BALB CPlant ExtractsSapotaceaeAnti-Inflammatory AgentsCarrageenanLipopolysaccharidesPlant ExtractsAnti-inflammatoryChrysophyllum cainitoLipopolysaccharideLupeol acetateMacrophages

Identifiers

PMID33725283
OpenAlexW3136667003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.