Evidence map›Paper›PMID 33725191›Full record

ArticleEJNMMI research2021

GMP-compliant fully automated radiosynthesis of [

Chi-Wei Chang, Chuang-Hsin Chiu, Ming-Hsien Lin, Hung-Ming Wu, Tsung-Hsun Yu, Pao-Yeh Wang, Yu-Yeh Kuo, Ya-Yao Huang, Chyng-Yann Shiue, Wen-Sheng Huang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Chi-Wei ChangDepartment of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Chuang-Hsin Chiu *Department of Nuclear Medicine, Tri-Service General Hospital, Taipei, Taiwan.
Ming-Hsien LinDepartment of Nuclear Medicine, Cheng Hsin General Hospital, Taipei, Taiwan.
Hung-Ming WuDepartment of Neurology, Changhua Christian Hospital, Changhua, Taiwan.
Tsung-Hsun YuBrain Research Center, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong Street, Taipei, 112, Taiwan.
Pao-Yeh WangBrain Research Center, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong Street, Taipei, 112, Taiwan.
Yu-Yeh KuoBrain Research Center, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong Street, Taipei, 112, Taiwan.
Ya-Yao HuangPET Center, Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, 100, Taiwan.
Chyng-Yann ShiueMolecular Imaging Center, National Taiwan University, Taipei, Taiwan.
Wen-Sheng Huang *Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Skye Hsin-Hsien YehBrain Research Center, National Yang Ming Chiao Tung University, No. 155, Sec. 2, Linong Street, Taipei, 112, Taiwan. skyeyeh@live.com.ORCID http://orcid.org/0000-0002-7495-1146
National Yang Ming Chiao Tung University · TWTri-Service General Hospital · TWChanghua Christian Hospital · TWCheng Hsin General Hospital · TWNational Taiwan University · TWTaipei Medical University Hospital · TWTzu Chi University · TW

Funding

Medical Affairs Bureau of the Ministry of National Defense MAB-108-053Ministry of Science and Technology R.O.C. MOST 106-2314-B-010 -012 -MY3Ministry of Science and Technology R.O.C. MOST 106-2314-B-075 -014 -MY3Ministry of Science and Technology R.O.C. MOST 107-2314-B-532 -003 -MY3
6 · The paper itself

Abstract

backgroundExpression of translocator protein (TSPO) on the outer mitochondrial membrane of activated microglia is strongly associated with neuroinflammation. The second-generation PET ligand [

resultsThe fully automated [

conclusionsBased on the current data on ligand specificity and selectivity in central tissues using 7 T PET/MR imaging, we demonstrate that [

Indexed as

[18F]FEPPAAnimal PETMR imagingNeuroinflammationTSPO

Identifiers

PMID33725191
PMCPMC7966678
OpenAlexW3137683615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.