Evidence map›Paper›PMID 33725000›Full record

ArticlePloS one2021

Taking account of asymptomatic infections: A modeling study of the COVID-19 outbreak on the Diamond Princess cruise ship.

Li-Shan Huang, Li Li, Lucia Dunn, Mai He

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Methodology of Epidemic Risk Analysis in the Naval Military.International journal of environmental research and public health · 2025
    Review
  4. Article
  5. COVID-19 outbreaks on ships: Analysis of three representative cases.Public health in practice (Oxford, England) · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. COVID-19's U.S. Temperature Response Profile.Environmental & resource economics · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Li-Shan HuangInstitute of Statistics, National Tsing Hua University, Hsinchu, Taiwan.ORCID 0000-0001-8297-2804
Li LiAT&T, Bedminster, New Jersey, United States of America.
Lucia DunnDepartment of Economics, The Ohio State University, Columbus, Ohio, United States of America.
Mai HeDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.
AT&T (United States) · USNational Tsing Hua University · TWThe Ohio State University · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 outbreak on the Diamond Princess (DP) cruise ship has provided empirical data to study the transmission potential of COVID-19 with the presence of pre/asymptomatic cases. We studied the changes in R0 on DP from January 21 to February 19, 2020 based on chain binomial models under two scenarios: no quarantine assuming a random mixing condition, and quarantine of passengers in cabins-passengers may get infected either by an infectious case in a shared cabin or by pre/asymptomatic crew who continued to work. Estimates of R0 at the beginning of the epidemic were 3.27 (95% CI, 3.02-3.54) and 3.78 (95% CI, 3.49-4.09) respectively for serial intervals of 5 and 6 days; and when quarantine started, with the reported asymptomatic ratio 0.505, R0 rose to 4.18 (95%CI, 3.86-4.52) and 4.73 (95%CI, 4.37-5.12) respectively for passengers who might be exposed to the virus due to pre/asymptomatic crew. Results confirm that the higher the asymptomatic ratio is, the more infectious contacts would happen. We find evidence to support a US CDC report that "a high proportion of asymptomatic infections could partially explain the high attack rate among cruise ship passengers and crew." Our study suggests that if the asymptomatic ratio is high, the conventional quarantine procedure may not be effective to stop the spread of virus.

Indexed as

Models, StatisticalAsymptomatic InfectionsCOVID-19Disease OutbreaksHumansQuarantineSARS-CoV-2Ships

Identifiers

PMID33725000
PMCPMC7963096
OpenAlexW3138098027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.