Evidence map›Paper›PMID 33724798›Full record

ArticleBioconjugate chemistry2021

New Bifunctional Chelators Incorporating Dibromomaleimide Groups for Radiolabeling of Antibodies with Positron Emission Tomography Imaging Radioisotopes.

Matthew Farleigh, Truc Thuy Pham, Zilin Yu, Jana Kim, Kavitha Sunassee, George Firth, Nafsika Forte, Vijay Chudasama, James R Baker, Nicholas J Long and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Site-SpecificBioconjugate chemistry · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Matthew FarleighSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London SE1 7EH, U.K.
Truc Thuy PhamSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London SE1 7EH, U.K.
Zilin YuSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London SE1 7EH, U.K.
Jana KimSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London SE1 7EH, U.K.
Kavitha SunasseeSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London SE1 7EH, U.K.
George FirthSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London SE1 7EH, U.K.
Nafsika ForteDepartment of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ, U.K.ORCID 0000-0002-8550-160X
Vijay ChudasamaDepartment of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ, U.K.ORCID 0000-0002-8876-3285
James R BakerDepartment of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ, U.K.ORCID 0000-0002-7223-2279
Nicholas J LongDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub, London W12 0BZ, U.K.ORCID 0000-0002-8298-938X
Charlotte RivasSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London SE1 7EH, U.K.
Michelle T MaSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, London SE1 7EH, U.K.ORCID 0000-0002-3349-7346
St Thomas' Hospital · GBUniversity College London · GBImperial College London · GB

Funding

British Heart Foundation IG/16/2/32273Cancer Research UK 24959Cancer Research UK C63178/A24959Wellcome TrustWellcome Trust 202762/Z/16/ZWellcome Trust 212885/Z/18/ZWellcome Trust WT088641/Z/09/Z
6 · The paper itself

Abstract

Positron Emission Tomography (PET) imaging with antibody-based contrast agents frequently uses the radioisotopes [

Indexed as

AnimalsBromine CompoundsChelating AgentsHumansPositron-Emission TomographyRadioisotopesBromine CompoundsChelating AgentsRadioisotopes

Identifiers

PMID33724798
PMCPMC8299457
OpenAlexW3136394584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.