Evidence map›Paper›PMID 33724773›Full record

ArticleACS infectious diseases2021

Robenidine Analogues Are Potent Antimalarials in Drug-Resistant

Alina Krollenbrock, Yuexin Li, Jane Xu Kelly, Michael K Riscoe

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Isopropoxy Benzene Guanidine AmelioratesInternational journal of molecular sciences · 2023
    Article
  4. Mononuclear/Binuclear [VACS omega · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alina KrollenbrockDepartment of Chemical Physiology and Biochemistry, Oregon Health & Science University, 3181 Sam Jackson Boulevard, Portland, Oregon 97239, United States.ORCID 0000-0003-3460-0808
Yuexin LiVA Medical Center, 3710 SW US Veterans Hospital Road, Portland, Oregon 97239, United States.
Jane Xu KellyVA Medical Center, 3710 SW US Veterans Hospital Road, Portland, Oregon 97239, United States.ORCID 0000-0001-8871-0207
Michael K RiscoeDepartment of Molecular Microbiology and Immunology, Oregon Health & Science University, 3181 Sam Jackson Boulevard, Portland, Oregon 97239, United States.ORCID 0000-0002-1343-5279
Oregon Health & Science University · USPortland VA Medical Center · US

Funding

Optimizing ELQs for Treatment and Prevention of MalariaR01AI100569 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI Michael Kevin RISCOE · 2014 to 2026
$8.0M
INTERACTIONS AT THE MICROBE/HOST INTERFACET32AI007472 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LANDFEAR, SCOTT M · 1995 to 2019
$6.7M
Development of a Sustained Release Injectable Formulation for Long-Term Delivery of ELQsR01AI141412 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI RISCOE, MICHAEL KEVIN · 2019 to 2022
$3.2M
Optimizing Pharmachins for Treatment and Prevention of Drug Resistant MalariaI01BX001421 · VA · PORTLAND VA MEDICAL CENTER · PI RISCOE, MICHAEL KEVIN · 2012 to 2015
–
Pharmachin Optimization and TestingI01BX003312 · VA · PORTLAND VA MEDICAL CENTER · PI RISCOE, MICHAEL KEVIN · 2016 to 2025
–
BLR&D Research Career Scientist Renewal Award ApplicationIK6BX004857 · VA · PORTLAND VA MEDICAL CENTER · PI Michael Kevin RISCOE · 2020 to 2026
–
BLRD VA I01 BX001421BLRD VA I01 BX003312BLRD VA IK6 BX004857NIAID NIH HHS R01 AI100569NIAID NIH HHS R01 AI141412NIAID NIH HHS T32 AI007472
6 · The paper itself

Abstract

Robenidine is a veterinary drug used in the poultry industry to treat coccidiosis caused by parasites in the

Indexed as

AntimalarialsMalariaPharmaceutical PreparationsAnimalsMicePlasmodium falciparumRobenidineAntimalarialsPharmaceutical PreparationsRobenidineaminoguanidinecoccidiosisEimeriamalariaPlasmodiumrobenidine

Identifiers

PMID33724773
PMCPMC8273112
OpenAlexW3136155890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.