Evidence map›Paper›PMID 33724743›Full record

ArticleHead and Neck Tumor Segmentation : First Challenge, HECKTOR 2020, Held in Conjunction with MICCAI 2020, Lima, Peru, October 4, 2020, Proceedings2021

Tumor Segmentation in Patients with Head and Neck Cancers Using Deep Learning Based-on Multi-modality PET/CT Images.

Mohamed A Naser, Lisanne V van Dijk, Renjie He, Kareem A Wahid, Clifton D Fuller

Abstract read
In one paragraph

Article in Head and Neck Tumor Segmentation : First Challenge, HECKTOR 2020, Held in Conjunction with MICCAI 2020, Lima, Peru, October 4, 2020, Proceedings, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Gradient Map-Assisted Head and Neck Tumor Segmentation: A Pre-RT to Mid-RT Approach in MRI-Guided Radiotherapy.Head and Neck Tumor Segmentation for MR-Guided Applications : First MICCAI Challenge, HNTS-MRG 2024, held in conjunction with MICCAI 2024, Marrakesh, Morocco, October 17, 2024, proceedings · 2025
    Article
  6. Head and neck tumor segmentation from [Physics in medicine and biology · 2024
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Progression Free Survival Prediction for Head and Neck Cancer Using Deep Learning Based on Clinical and PET/CT Imaging Data.Head and neck tumor segmentation and outcome prediction : second challenge, HECKTOR 2021, held in conjunction with MICCAI 2021, Strasbourg, France, September 27, 2021, Proceedings. Head and Neck Tumor Segmentation Challenge (2nd : 2021 ... · 2022
    Article
  17. Head and Neck Cancer Primary Tumor Auto Segmentation Using Model Ensembling of Deep Learning in PET/CT Images.Head and neck tumor segmentation and outcome prediction : second challenge, HECKTOR 2021, held in conjunction with MICCAI 2021, Strasbourg, France, September 27, 2021, Proceedings. Head and Neck Tumor Segmentation Challenge (2nd : 2021 ... · 2022
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohamed A NaserDepartment of Radiation Oncology, The University of Texas MD AndersonCancer, Houston, TX 77030, USA
Lisanne V van DijkDepartment of Radiation Oncology, The University of Texas MD AndersonCancer, Houston, TX 77030, USA
Renjie HeDepartment of Radiation Oncology, The University of Texas MD AndersonCancer, Houston, TX 77030, USA
Kareem A WahidDepartment of Radiation Oncology, The University of Texas MD AndersonCancer, Houston, TX 77030, USA
Clifton D FullerDepartment of Radiation Oncology, The University of Texas MD AndersonCancer, Houston, TX 77030, USA

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Targeting the p53 pathway for reversal of oral premalignancyP50CA097007 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MYERS, JEFFREY NICHOLAS · 2002 to 2012
$26.1M
Development of functional magnetic resonance imaging-guided adaptive radiotherapy for head and neck cancer patients using novel MR-Linac deviceR01DE028290 · NIDCR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CHRISTODOULEAS, JOHN PAUL, FULLER, CLIFTON DAVID · 2019 to 2023
$4.3M
NRSA Training CoreTL1TR003169 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CHANDRA, JOYA, FROST, JEFFREY A. · 2019 to 2023
$3.7M
SCH: Personalized Rescheduling of Adaptive Radiation Therapy for Head & Neck CancerR01CA257814 · NCI · RICE UNIVERSITY · PI FULLER, CLIFTON DAVID, SCHAEFER, ANDREW J · 2021 to 2024
$1.8M
SMART-ACT: Spatial Methodologic Approaches for Risk Assessment and Therapeutic Adaptation in Cancer TreatmentR01CA214825 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CANAHUATE, GUADALUPE, FULLER, CLIFTON DAVID · 2017 to 2019
$1.1M
imaging Radiation-Associated Dysphagia (iRAD)R01CA218148 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI FULLER, CLIFTON DAVID, HUTCHESON, KATHERINE ARNOLD · 2017 to 2019
$810k
QuBBD: Precision E –Radiomics for Dynamic Big Head & Neck Cancer Data R01CA225190 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CANAHUATE, GUADALUPE, FULLER, CLIFTON DAVID · 2017 to 2019
$776k
Fellow and Resident Radiation Oncology iNtensive Training in Imaging and Informatics to Empower Research Careers (FRONTI2ER)R25EB025787 · NIBIB · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DAS, PRAJNAN, FULLER, CLIFTON DAVID · 2018 to 2022
$535k
Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Establish Objective Clinical Outcome Measures for Mandibular OsteoradionecrosisR56DE025248 · NIDCR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LAI, STEPHEN Y · 2015 to 2015
$470k
NCATS NIH HHS TL1 TR003169NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA097007NCI NIH HHS R01 CA214825NCI NIH HHS R01 CA218148NCI NIH HHS R01 CA225190NCI NIH HHS R01 CA257814NIBIB NIH HHS R25 EB025787NIDCR NIH HHS R01 DE028290NIDCR NIH HHS R56 DE025248
6 · The paper itself

Abstract

Segmentation of head and neck cancer (HNC) primary tumors onmedical images is an essential, yet labor-intensive, aspect of radiotherapy.PET/CT imaging offers a unique ability to capture metabolic and anatomicinformation, which is invaluable for tumor detection and border definition. Anautomatic segmentation tool that could leverage the dual streams of informationfrom PET and CT imaging simultaneously, could substantially propel HNCradiotherapy workflows forward. Herein, we leverage a multi-institutionalPET/CT dataset of 201 HNC patients, as part of the MICCAI segmentationchallenge, to develop novel deep learning architectures for primary tumor auto-segmentation for HNC patients. We preprocess PET/CT images by normalizingintensities and applying data augmentation to mitigate overfitting. Both 2D and3D convolutional neural networks based on the U-net architecture, which wereoptimized with a model loss function based on a combination of dice similaritycoefficient (DSC) and binary cross entropy, were implemented. The median andmean DSC values comparing the predicted tumor segmentation with the groundtruth achieved by the models through 5-fold cross validation are 0.79 and 0.69for the 3D model, respectively, and 0.79 and 0.67 for the 2D model, respec-tively. These promising results show potential to provide an automatic, accurate,and efficient approach for primary tumor auto-segmentation to improve theclinical practice of HNC treatment.

Indexed as

Auto-contouringCTDeep learningHead and neck cancerPETTumor segmentation

Identifiers

PMID33724743
PMCPMC7929493

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.