ArticleGenetics2021
The rates of introgression and barriers to genetic exchange between hybridizing species: sex chromosomes vs autosomes.
Article in Genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
- Widespread introgression and a potential role for a neo-sex chromosome in booby diversification and speciation.bioRxiv : the preprint server for biology · 2026Article
- Evolutionary rate correlations reveal long-term co-evolutionary interactions inbioRxiv : the preprint server for biology · 2026Article
- Introgression across Narrow Contact Zones Shapes the Genomic Landscape of Phylogenetic Variation in an African Bird Clade.Systematic biology · 2025Article
- Speciation Genomics in the Tiger Whiptail Lizards (Aspidoscelis tigris Complex).Genome biology and evolution · 2025Article
- The Tree of Sex consortium: a global initiative for studying the evolution of reproduction in eukaryotes.Journal of evolutionary biology · 2025Article
- Genome-Wide Demographic Analyses of Balaenid Whales Revealed Complex History of Gene Flow Associated with Past Climate Oscillation.Genome biology and evolution · 2025Article
- Genomic data reveal a north-south split and introgression history of blood fluke populations across Africa.Nature communications · 2025Article
- Increased Evolutionary Rate in the Z chromosome of Sympatric and Allopatric Species of Morpho Butterflies.Genome biology and evolution · 2024Article
- Beyond Haldane's rule: Sex-biased hybrid dysfunction for all modes of sex determination.eLife · 2024Review
- Recent secondary contact, genome-wide admixture, and asymmetric introgression of neo-sex chromosomes between two Pacific island bird species.PLoS genetics · 2024Article
- Do genetic loci that cause reproductive isolation in the lab inhibit gene flow in nature?Evolution; international journal of organic evolution · 2024Article
- Inference of selective forces on house mouse genomes during secondary contact in East Asia.Genome research · 2024Article
- Enrichment of hard sweeps on the X chromosome compared to autosomes in six Drosophila species.Genetics · 2024Article
- Enrichment of hard sweeps on the X chromosome compared to autosomes in six Drosophila species.bioRxiv : the preprint server for biology · 2023Article
- Restricted X chromosome introgression and support for Haldane's rule in hybridizing damselflies.Proceedings. Biological sciences · 2022Article
- A genetic switch for male UV iridescence in an incipient species pair of sulphur butterflies.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Bidirectional Introgression between Mus musculus domesticus and Mus spretus.Genome biology and evolution · 2022Article
- Hybrid Sterility, Genetic Conflict and Complex Speciation: Lessons From theFrontiers in genetics · 2021Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interspecific crossing experiments have shown that sex chromosomes play a major role in reproductive isolation between many pairs of species. However, their ability to act as reproductive barriers, which hamper interspecific genetic exchange, has rarely been evaluated quantitatively compared to Autosomes. This genome-wide limitation of gene flow is essential for understanding the complete separation of species, and thus speciation. Here, we develop a mainland-island model of secondary contact between hybridizing species of an XY (or ZW) sexual system. We obtain theoretical predictions for the frequency of introgressed alleles, and the strength of the barrier to neutral gene flow for the two types of chromosomes carrying multiple interspecific barrier loci. Theoretical predictions are obtained for scenarios where introgressed alleles are rare. We show that the same analytical expressions apply for sex chromosomes and autosomes, but with different sex-averaged effective parameters. The specific features of sex chromosomes (hemizygosity and absence of recombination in the heterogametic sex) lead to reduced levels of introgression on the X (or Z) compared to autosomes. This effect can be enhanced by certain types of sex-biased forces, but it remains overall small (except when alleles causing incompatibilities are recessive). We discuss these predictions in the light of empirical data comprising model-based tests of introgression and cline surveys in various biological systems.
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