Evidence map›Paper›PMID 33724196›Full record

ArticleJMIR medical informatics2021

Hybrid Deep Learning for Medication-Related Information Extraction From Clinical Texts in French: MedExt Algorithm Development Study.

Jordan Jouffroy, Sarah F Feldman, Ivan Lerner, Bastien Rance, Anita Burgun, Antoine Neuraz

Abstract read
In one paragraph

Article in JMIR medical informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. AI-Based Automation for Medication Reconciliation: Scoping Review.Journal of medical Internet research · 2026
    Article
  4. Efficient extraction of medication information from clinical notes: an evaluation in 2 languages.Journal of the American Medical Informatics Association : JAMIA · 2025
    Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jordan JouffroyDepartment of Biomedical Informatics, Necker-Enfants malades Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.ORCID https://orcid.org/0000-0001-5899-5969
Sarah F FeldmanDepartment of Biomedical Informatics, Necker-Enfants malades Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.ORCID https://orcid.org/0000-0001-8264-5184
Ivan LernerDepartment of Biomedical Informatics, Necker-Enfants malades Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.ORCID https://orcid.org/0000-0002-5466-1707
Bastien RanceUMRS 1138 team 22, Institut National de la Santé et de la Recherche Médicale, Université de Paris, Paris, France.ORCID https://orcid.org/0000-0003-4417-1197
Anita BurgunDepartment of Biomedical Informatics, Necker-Enfants malades Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.ORCID https://orcid.org/0000-0001-6855-4366
Antoine NeurazDepartment of Biomedical Informatics, Necker-Enfants malades Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.ORCID https://orcid.org/0000-0001-7142-6728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInformation related to patient medication is crucial for health care; however, up to 80% of the information resides solely in unstructured text. Manual extraction is difficult and time-consuming, and there is not a lot of research on natural language processing extracting medical information from unstructured text from French corpora.

objectiveWe aimed to develop a system to extract medication-related information from clinical text written in French.

methodsWe developed a hybrid system combining an expert rule-based system, contextual word embedding (embedding for language model) trained on clinical notes, and a deep recurrent neural network (bidirectional long short term memory-conditional random field). The task consisted of extracting drug mentions and their related information (eg, dosage, frequency, duration, route, condition). We manually annotated 320 clinical notes from a French clinical data warehouse to train and evaluate the model. We compared the performance of our approach to those of standard approaches: rule-based or machine learning only and classic word embeddings. We evaluated the models using token-level recall, precision, and F-measure.

resultsThe overall F-measure was 89.9% (precision 90.8; recall: 89.2) when combining expert rules and contextualized embeddings, compared to 88.1% (precision 89.5; recall 87.2) without expert rules or contextualized embeddings. The F-measures for each category were 95.3% for medication name, 64.4% for drug class mentions, 95.3% for dosage, 92.2% for frequency, 78.8% for duration, and 62.2% for condition of the intake.

conclusionsAssociating expert rules, deep contextualized embedding, and deep neural networks improved medication information extraction. Our results revealed a synergy when associating expert knowledge and latent knowledge.

Indexed as

deep learningelectronic health recordshybrid systemmedication informationnatural language processingrule-based system, recurrent neural network

Identifiers

PMID33724196
PMCPMC8077811

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.