Evidence map›Paper›PMID 33724180›Full record

ArticleeLife2021

Selective dendritic localization of mRNA in

Jessica Mitchell, Carlas S Smith, Josh Titlow, Nils Otto, Pieter van Velde, Martin Booth, Ilan Davis, Scott Waddell

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Circular RNAScience advances · 2026
    Article
  2. Article
  3. Article
  4. Pairing-Dependent Plasticity in a Dissected Fly Brain Is Input-Specific and Requires Synaptic CaMKII Enrichment and Nighttime Sleep.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  5. eLife · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Jessica MitchellCentre for Neural Circuits and Behaviour, University of Oxford, Oxford, United Kingdom.
Carlas S SmithCentre for Neural Circuits and Behaviour, University of Oxford, Oxford, United Kingdom.
Josh TitlowDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.
Nils OttoCentre for Neural Circuits and Behaviour, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-9713-4088
Pieter van VeldeDelft Center for Systems and Control, Delft University of Technology, Delft, Netherlands.ORCID 0000-0002-7281-8026
Martin BoothCentre for Neural Circuits and Behaviour, University of Oxford, Oxford, United Kingdom.
Ilan DavisDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-5385-3053
Scott WaddellCentre for Neural Circuits and Behaviour, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-4503-6229
University of Oxford · GBDelft University of Technology · NL

Funding

Medical Research Council MR/K01577X/1Wellcome Trust 091911Wellcome Trust 096144Wellcome Trust 107457Wellcome Trust 200846/Z/16/ZWellcome Trust 203261/Z/16/ZWellcome Trust 209412Wellcome Trust 209412/Z/17/Z
6 · The paper itself

Abstract

Memory-relevant neuronal plasticity is believed to require local translation of new proteins at synapses. Understanding this process requires the visualization of the relevant mRNAs within these neuronal compartments. Here, we used single-molecule fluorescence in situ hybridization to localize mRNAs at subcellular resolution in the adult

Indexed as

AnimalsBrainCalcium-Calmodulin-Dependent Protein Kinase Type 2Conditioning, ClassicalDendritesDrosophilaDrosophila ProteinsIn Situ Hybridization, FluorescenceLearningMushroom BodiesNeuronal PlasticityNeuronsReceptors, NicotinicRNA, MessengerSynapsesCalcium-Calmodulin-Dependent Protein Kinase Type 2Drosophila ProteinsReceptors, NicotinicRNA, MessengerdendriteD. melanogastermemorymRNA localisationneural circuitryneuroscience

Identifiers

PMID33724180
PMCPMC8004107
OpenAlexW3137762867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.