Evidence map›Paper›PMID 33724179›Full record

ArticleeLife2021

Increased longevity due to sexual activity in mole-rats is associated with transcriptional changes in the HPA stress axis.

Arne Sahm, Matthias Platzer, Philipp Koch, Yoshiyuki Henning, Martin Bens, Marco Groth, Hynek Burda, Sabine Begall, Saskia Ting, Moritz Goetz and 7 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Dehydroepiandrosterone (DHEA) as a tool for conservation.Environmental monitoring and assessment · 2026
    Review
  2. Article
  3. Article
  4. Facing stress and inflammation: From the cell to the planet.World journal of experimental medicine · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Stress in an underground empire.Biology letters · 2022
    Review
  13. The Interrelationship Between Female Reproductive Aging and Survival.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Review
  14. Article
  15. Alternative Animal Models of Aging Research.Frontiers in molecular biosciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Arne SahmComputational Biology Group, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.ORCID https://orcid.org/0000-0002-7330-1790
Matthias PlatzerComputational Biology Group, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.ORCID http://orcid.org/0000-0003-0596-8582
Philipp KochCore Facility Life Science Computing, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.ORCID http://orcid.org/0000-0003-2825-7943
Yoshiyuki HenningInstitute of Physiology, University Hospital, University of Duisburg-Essen, Essen, Germany.ORCID https://orcid.org/0000-0002-0166-2204
Martin BensCore Facility Sequencing, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.ORCID http://orcid.org/0000-0001-7940-6668
Marco GrothCore Facility Sequencing, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.ORCID http://orcid.org/0000-0002-9199-8990
Hynek BurdaDepartment of General Zoology, Faculty of Biology, University of Duisburg-Essen, Essen, Germany.
Sabine BegallDepartment of General Zoology, Faculty of Biology, University of Duisburg-Essen, Essen, Germany.ORCID http://orcid.org/0000-0001-9907-6387
Saskia TingInstitute of Pathology and Neuropathology, University Hospital, University of Duisburg-Essen, Essen, Germany.
Moritz GoetzInstitute of Pathology and Neuropathology, University Hospital, University of Duisburg-Essen, Essen, Germany.
Paul Van DaeleDepartment of Zoology, University of South Bohemia, České Budějovice, Czech Republic.
Magdalena StaniszewskaDepartment of Nuclear Medicine, University Hospital, University of Duisburg-Essen, Essen, Germany.
Jasmin Mona KloseDepartment of Nuclear Medicine, University Hospital, University of Duisburg-Essen, Essen, Germany.
Pedro Fragoso CostaDepartment of Nuclear Medicine, University Hospital, University of Duisburg-Essen, Essen, Germany.
Steve Hoffmann *Computational Biology Group, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.
Karol Szafranski *Core Facility Life Science Computing, Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany.ORCID http://orcid.org/0000-0001-6391-1766
Philip Dammann *Department of General Zoology, Faculty of Biology, University of Duisburg-Essen, Essen, Germany.ORCID https://orcid.org/0000-0002-0624-3965
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) · DEUniversity of Duisburg-Essen · DECzech Academy of Sciences, Institute of Physiology · CZCzech University of Life Sciences Prague · CZUniversity of South Bohemia in České Budějovice · CZ

Funding

Deutsche Forschungsgemeinschaft DA 992/3-1Deutsche Forschungsgemeinschaft PL 173/8-1Deutsche Forschungsgemeinschaft Research Training Group 1739
6 · The paper itself

Abstract

Sexual activity and/or reproduction are associated with a doubling of life expectancy in the long-lived rodent genus

Indexed as

ReproductionAnimalsDehydroepiandrosteroneFemaleGene ExpressionHypothalamo-Hypophyseal SystemInsulin-Like Growth Factor ILongevityMaleMole RatsPituitary-Adrenal SystemSexual Behavior, AnimalStress, PsychologicalDehydroepiandrosteroneInsulin-Like Growth Factor IACTHRchromosomescomputational biologyDHEAdifferential gene expressionFukomysgene expressionhypothalamic-pituitary-adrenal axislifespansystems biology

Identifiers

PMID33724179
PMCPMC8012063
OpenAlexW3137485978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.