Evidence map›Paper›PMID 33723966›Full record

ArticleMikrochimica acta2021

A sensitive electrochemiluminescence DNA biosensor based on the signal amplification of ExoIII enzyme-assisted hybridization chain reaction combined with nanoparticle-loaded multiple probes.

Hong Hai, Ciping Chen, Dongli Chen, Peijun Li, Yang Shan, Jianping Li

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hong HaiGuangxi Key Laboratory of Electrochemical and Magnetochemical Function Materials, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, Guangxi, China.
Ciping ChenGuangxi Key Laboratory of Electrochemical and Magnetochemical Function Materials, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, Guangxi, China.
Dongli ChenGuangxi Key Laboratory of Electrochemical and Magnetochemical Function Materials, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, Guangxi, China.
Peijun LiGuangxi Key Laboratory of Electrochemical and Magnetochemical Function Materials, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, Guangxi, China.
Yang ShanGuangxi Key Laboratory of Electrochemical and Magnetochemical Function Materials, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, Guangxi, China.
Jianping LiGuangxi Key Laboratory of Electrochemical and Magnetochemical Function Materials, College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, 541004, Guangxi, China. likianping@263.net.ORCID 0000-0001-8920-3223

Funding

National Natural Science Foundation of China 21765006Natural Science Foundation of Guangxi Province 2018GXNSFAA050023
6 · The paper itself

Abstract

An electrochemiluminescence (ECL) DNA biosensor based on ExoIII exonuclease assistance and hybridization chain reaction (HCR) amplification technology has been constructed. ExoIII exonuclease and triple-helix DNA molecular switch are used in detecting a target in circulation. By combining HCR with AuNPs@DNA, a novel signal probe is built, which enables multiple signal amplification and the high-sensitive detection of transgenic rice BT63 DNA. The Fe

Indexed as

Bacillus thuringiensis ToxinsBiosensing TechniquesDNA, BacterialDNA ProbesElectrochemical TechniquesElectrodesEndotoxinsExodeoxyribonucleasesGoldHemolysin ProteinsImmobilized Nucleic AcidsLimit of DetectionLuminescent AgentsLuminescent MeasurementsMagnetite NanoparticlesNucleic Acid HybridizationBacillus thuringiensis ToxinsDNA, BacterialDNA ProbesEndotoxinsexodeoxyribonuclease IIIExodeoxyribonucleasesGoldHemolysin ProteinsImmobilized Nucleic Acidsinsecticidal crystal protein, Bacillus ThuringiensisLuminescent AgentsMagnetite NanoparticlesOrganometallic Compoundstris(2,2'-bipyridyl)ruthenium(II)DNA biosensorElectrochemiluminescenceExonucleaseHybridization chain reactionSignal amplificationTriple-helix DNA molecular switch

Identifiers

PMID33723966

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.